Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WYR1 / PI3R5_HUMAN
Protein Name Phosphoinositide 3-kinase regulatory subunit 5
Gene Name Name: PIK3R5
Organism Homo sapiens (Human)

PRO ID PR:Q8WYR1
DAG View
PRO Name phosphoinositide 3-kinase regulatory subunit 5 (human)
Definition A phosphoinositide 3-kinase regulatory subunit 5 that is encoded in the genome of human.
Short Label hPIK3R5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WYR1 (PIK3R5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T114 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus   UniProt 19369195
S468 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus   UniProt 19369195
K562 Ubiquitination PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus
K782 Acetylation PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S432 R432 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:1324 / lung cancer [ tcga ]
S458 C458 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S458 R458 Biomuta DOID:3571 / liver cancer [ icgc ]
K825 N825 Biomuta DOID:363 / uterine cancer [ tcga ]