iPTMnet Report for Q8WYP5 (AHCTF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WYP5 / ELYS_HUMAN
Protein Name Protein ELYS
Gene Name Name: AHCTF1
Synonyms:ELYS,TMBS62;ORFNames:MSTP108;
Organism Homo sapiens (Human)

PRO ID PR:Q8WYP5
DAG View
PRO Name protein ELYS (human)
Definition An AT-hook-containing transcription factor 1 that is encoded in the genome of human.
Short Label hAHCTF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WYP5 (AHCTF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K42 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
C481 Methylation IEDB 31844290
T501 Phosphorylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K505 Methylation PhosphoSitePlus
K505 Ubiquitination PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus   UniProt 23186163
S528 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 20068231, ...18220336
S537 Phosphorylation phospho.ELM 18669648, 16565220, 18220336
C610 Methylation IEDB 31844290
C664 Methylation IEDB 31844290
K717 Ubiquitination PhosphoSitePlus
R735 Methylation PhosphoSitePlus
K738 Ubiquitination PhosphoSitePlus
T747 Phosphorylation PhosphoSitePlus
S871 Phosphorylation IEDB 32387766
K969 Ubiquitination PhosphoSitePlus
K975 Ubiquitination PhosphoSitePlus
S995 Phosphorylation PhosphoSitePlus
K1002 Ubiquitination PhosphoSitePlus
K1017 Acetylation PhosphoSitePlus
K1017 Ubiquitination PhosphoSitePlus
S1022 Phosphorylation PhosphoSitePlus
K1041 Ubiquitination PhosphoSitePlus
T1050 Phosphorylation PhosphoSitePlus
K1069 Ubiquitination PhosphoSitePlus
T1075 Phosphorylation PhosphoSitePlus
T1076 Phosphorylation PhosphoSitePlus
S1080 Phosphorylation PhosphoSitePlus
K1082 Ubiquitination PhosphoSitePlus
S1087 Phosphorylation PhosphoSitePlus
T1105 Phosphorylation PhosphoSitePlus
S1108 Phosphorylation PhosphoSitePlus
K1109 Ubiquitination PhosphoSitePlus
S1129 Phosphorylation PhosphoSitePlus
S1132 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus
K1141 Ubiquitination PhosphoSitePlus
S1142 Phosphorylation PhosphoSitePlus   UniProt 18669648, 21406692
Y1145 Phosphorylation PhosphoSitePlus
S1148 Phosphorylation PhosphoSitePlus
S1150 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1153 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1154 Phosphorylation PhosphoSitePlus
S1155 Phosphorylation PhosphoSitePlus   UniProt 18669648
K1158 Ubiquitination PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
S1168 Phosphorylation PhosphoSitePlus
T1175 Phosphorylation PhosphoSitePlus   UniProt 18669648
K1183 Acetylation PhosphoSitePlus
S1188 O-Glycosylation GlyGen 28411811, 30379171, 33214551, ...34019948, 32119511, 33465208
T1191 Phosphorylation PhosphoSitePlus
S1192 O-Glycosylation GlyGen 33465208
T1198 Phosphorylation PhosphoSitePlus
S1201 Phosphorylation PhosphoSitePlus
S1205 O-Glycosylation GlyGen 33465208
S1205 Phosphorylation PhosphoSitePlus
T1206 O-Glycosylation GlyGen 33465208
T1206 Phosphorylation PhosphoSitePlus
S1209 Phosphorylation PhosphoSitePlus
T1210 Phosphorylation PhosphoSitePlus
S1214 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 21406692, 15302935
S1216 Phosphorylation PhosphoSitePlus
S1218 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1222 Phosphorylation PhosphoSitePlus   UniProt 23186163, 18220336
T1229 Phosphorylation PhosphoSitePlus
S1232 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
K1241 Ubiquitination PhosphoSitePlus
S1250 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
K1251 Ubiquitination PhosphoSitePlus
T1256 Phosphorylation PhosphoSitePlus
T1257 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1259 Ubiquitination PhosphoSitePlus
K1260 Ubiquitination PhosphoSitePlus
S1272 Phosphorylation PhosphoSitePlus
T1276 Phosphorylation PhosphoSitePlus
S1278 Phosphorylation PhosphoSitePlus
S1283 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 19690332, 20068231
S1295 Phosphorylation PhosphoSitePlus
S1297 Phosphorylation PhosphoSitePlus   UniProt 20068231
K1300 Ubiquitination PhosphoSitePlus
S1304 Phosphorylation phospho.ELM 17525332
K1341 Ubiquitination PhosphoSitePlus
S1342 O-Glycosylation GlyGen 33465208
S1344 O-Glycosylation GlyGen 33465208
T1345 O-Glycosylation GlyGen 28411811, 30379171, 33214551, ...34019948, 32119511, 33465208
K1361 Ubiquitination PhosphoSitePlus
T1369 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S1371 Phosphorylation PhosphoSitePlus
K1375 Ubiquitination PhosphoSitePlus
S1402 Phosphorylation PhosphoSitePlus
T1436 Phosphorylation PhosphoSitePlus
T1442 Phosphorylation PhosphoSitePlus
S1452 Phosphorylation PhosphoSitePlus
K1507 Ubiquitination PhosphoSitePlus
S1511 Phosphorylation PhosphoSitePlus
S1513 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T1517 Phosphorylation PhosphoSitePlus   UniProt 21406692
K1527 Ubiquitination PhosphoSitePlus
S1533 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S1541 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...18669648, 19690332, 20068231
K1552 Ubiquitination PhosphoSitePlus
K1625 Ubiquitination PhosphoSitePlus
S1629 Phosphorylation PhosphoSitePlus
S1647 Phosphorylation PhosphoSitePlus
K1653 Ubiquitination PhosphoSitePlus
T1656 Phosphorylation PhosphoSitePlus
Y1659 Phosphorylation PhosphoSitePlus
K1665 Ubiquitination PhosphoSitePlus
K1677 Ubiquitination PhosphoSitePlus
K1682 Ubiquitination PhosphoSitePlus
K1712 Ubiquitination PhosphoSitePlus
K1716 Methylation PhosphoSitePlus
S1729 Phosphorylation PhosphoSitePlus   UniProt 18669648
T1764 Phosphorylation PhosphoSitePlus
K1766 Acetylation PhosphoSitePlus
S1771 Phosphorylation PhosphoSitePlus
K1780 Ubiquitination PhosphoSitePlus
S1786 Phosphorylation PhosphoSitePlus
Y1790 Phosphorylation PhosphoSitePlus
S1791 Phosphorylation PhosphoSitePlus
S1797 Phosphorylation PhosphoSitePlus
S1806 Phosphorylation PhosphoSitePlus   UniProt 18669648
T1808 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1827 Phosphorylation PhosphoSitePlus
S1846 Phosphorylation PhosphoSitePlus
S1847 O-Glycosylation GlyGen 28411811, 30379171, 33214551, ...34019948, 32119511, 33465208
T1857 O-Glycosylation GlyGen 33465208
T1858 O-Glycosylation GlyGen 33465208
S1866 Phosphorylation PhosphoSitePlus
T1868 Phosphorylation PhosphoSitePlus
T1871 Phosphorylation PhosphoSitePlus
S1878 Phosphorylation PhosphoSitePlus   UniProt 18691976, 18669648, 20068231
S1884 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332
S1894 O-Glycosylation GlyGen 33465208
T1895 O-Glycosylation GlyGen 33465208
T1897 O-Glycosylation GlyGen 33465208
S1898 Phosphorylation PhosphoSitePlus   UniProt 18669648, 20068231
S1900 O-Glycosylation GlyGen 28411811, 30379171, 33214551, ...34019948, 32119511, 33465208
S1900 Phosphorylation PhosphoSitePlus
S1908 Phosphorylation PhosphoSitePlus
S1914 Phosphorylation PhosphoSitePlus
T1917 Phosphorylation PhosphoSitePlus
S1925 Phosphorylation PhosphoSitePlus
S1926 Phosphorylation PhosphoSitePlus
S1944 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
S1946 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1952 Phosphorylation PhosphoSitePlus
S1988 Phosphorylation PhosphoSitePlus
S1996 Phosphorylation PhosphoSitePlus   UniProt 17081983
S2009 Phosphorylation PhosphoSitePlus
T2010 Phosphorylation PhosphoSitePlus
T2013 Phosphorylation PhosphoSitePlus
S2017 Phosphorylation PhosphoSitePlus
K2024 Acetylation PhosphoSitePlus
K2024 Ubiquitination PhosphoSitePlus
S2043 Phosphorylation PhosphoSitePlus   UniProt 20068231
S2044 Phosphorylation PhosphoSitePlus   UniProt 20068231
S2060 O-Glycosylation GlyGen 28411811, 30379171, 33214551, ...34019948, 32119511, 33465208
S2060 Phosphorylation PhosphoSitePlus   UniProt 18669648
S2063 O-Glycosylation GlyGen 33465208
S2063 Phosphorylation PhosphoSitePlus
S2065 O-Glycosylation GlyGen 33465208
S2065 Phosphorylation PhosphoSitePlus
T2087 Phosphorylation PhosphoSitePlus
S2089 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
T2091 Phosphorylation PhosphoSitePlus
K2092 Methylation PhosphoSitePlus
S2093 Phosphorylation PhosphoSitePlus
S2111 Phosphorylation PhosphoSitePlus
S2120 Phosphorylation PhosphoSitePlus   UniProt 18691976, 18669648, 20068231
S2123 Phosphorylation PhosphoSitePlus   UniProt 18669648
S2154 Phosphorylation PhosphoSitePlus   UniProt 18669648, 20068231
S2160 Phosphorylation PhosphoSitePlus
T2165 O-Glycosylation GlyGen 30379171
S2166 O-Glycosylation GlyGen 30379171
S2181 Phosphorylation PhosphoSitePlus
K2207 Ubiquitination PhosphoSitePlus
S2212 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S2222 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...19690332, 20068231
S2226 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...20068231
S2233 Phosphorylation PhosphoSitePlus
T2239 Phosphorylation PhosphoSitePlus
T2242 Phosphorylation PhosphoSitePlus
S2254 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S1177 Phosphorylation PhosphoSitePlus
S1230 Phosphorylation phospho.ELM 18669648
K1801 Acetylation PhosphoSitePlus
Y1825 Phosphorylation PhosphoSitePlus
T1843 Phosphorylation PhosphoSitePlus
S2044 Phosphorylation PhosphoSitePlus
T2274 Phosphorylation PhosphoSitePlus
T2277 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S537 Phosphorylation HPRD 18691976, 18669648, 19664994, ...20068231
S1004 Phosphorylation HPRD 19691289
T1056 Phosphorylation HPRD 20068231
T1059 Phosphorylation HPRD 20068231
S1089 Phosphorylation HPRD 20068231
S1096 Phosphorylation HPRD 20068231
T1114 Phosphorylation HPRD 20068231
S1151 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231
S1159 Phosphorylation HPRD 18669648, 20068231
S1163 Phosphorylation HPRD 18669648
S1164 Phosphorylation HPRD 18669648
S1169 Phosphorylation HPRD 18669648, 18491316, 19007248, ...20068231, 19691289
T1184 Phosphorylation HPRD 18669648
S1218 Phosphorylation HPRD 19691289
S1223 Phosphorylation HPRD 19651622, 19691289, 20068231
S1225 Phosphorylation HPRD 19651622, 19691289
S1227 Phosphorylation HPRD 19651622, 19691289, 20068231
S1231 Phosphorylation HPRD 19651622, 20068231
T1238 Phosphorylation HPRD 18669648, 20068231
S1241 Phosphorylation HPRD 17081983, 19691289, 18452278, ...18669648, 19007248, 20068231
S1259 Phosphorylation HPRD 18669648
T1265 Phosphorylation HPRD 18669648, 20068231
T1266 Phosphorylation HPRD 18669648
S1292 Phosphorylation HPRD 18691976, 18767875, 19664994, ...18452278, 19651622, 17322306, 18669648, 20068231
S1304 Phosphorylation HPRD 19651622, 17525332, 20068231
S1306 Phosphorylation HPRD 19651622, 20068231
S1320 Phosphorylation HPRD 18669648
T1322 Phosphorylation HPRD 18452278
S1323 Phosphorylation HPRD 18669648, 18452278
S1335 Phosphorylation HPRD 18452278
S1375 Phosphorylation HPRD 19651622, 20068231
T1378 Phosphorylation HPRD 18691976, 20068231
S1411 Phosphorylation HPRD 19007248
S1472 Phosphorylation HPRD 18691976
T1475 Phosphorylation HPRD 20068231
S1483 Phosphorylation HPRD 20068231
S1520 Phosphorylation HPRD 19007248
S1522 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
T1526 Phosphorylation HPRD 19651622, 20068231
S1542 Phosphorylation HPRD 18669648, 20068231
S1550 Phosphorylation HPRD 18691976, 17081983, 19664995, ...19691289, 19651622, 18669648, 20068231
T1629 Phosphorylation HPRD 19007248
S1701 Phosphorylation HPRD 19007248
S1738 Phosphorylation HPRD 18669648
S1746 Phosphorylation HPRD 19007248
T1773 Phosphorylation HPRD 19007248
S1780 Phosphorylation HPRD 19007248
S1806 Phosphorylation HPRD 18077418
S1815 Phosphorylation HPRD 18669648, 20068231
T1817 Phosphorylation HPRD 18669648, 20068231
S1887 Phosphorylation HPRD 18691976, 18669648, 20068231, ...18452278
S1893 Phosphorylation HPRD 18669648
T1906 Phosphorylation HPRD 20068231
S1907 Phosphorylation HPRD 18691976, 18669648, 19007248, ...20068231
S1909 Phosphorylation HPRD 20068231
S1953 Phosphorylation HPRD 18669648, 19007248, 19691289, ...20068231, 18212344
S1955 Phosphorylation HPRD 19691289, 20068231
S1961 Phosphorylation HPRD 19007248
S1992 Phosphorylation HPRD 20068231
S2005 Phosphorylation HPRD 17081983, 20068231
S2052 Phosphorylation HPRD 20068231
S2053 Phosphorylation HPRD 20068231
S2069 Phosphorylation HPRD 18669648, 19007248, 20068231
S2072 Phosphorylation HPRD 19007248
T2096 Phosphorylation HPRD 20068231
S2098 Phosphorylation HPRD 18669648, 20068231
T2100 Phosphorylation HPRD 20068231
S2129 Phosphorylation HPRD 18691976, 18669648, 20068231
S2132 Phosphorylation HPRD 18669648, 20068231
S2163 Phosphorylation HPRD 18669648, 20068231
S2221 Phosphorylation HPRD 18669648, 19691289, 20068231
S2231 Phosphorylation HPRD 19413330, 18691976, 16964243, ...19651622, 19691289, 19007248, 17322306, 18669648, 20068231
S2235 Phosphorylation HPRD 19413330, 18691976, 16964243, ...19651622, 19691289, 19007248, 17322306, 18669648, 20068231
T2247 Phosphorylation HPRD 19007248
T2251 Phosphorylation HPRD 19007248
S2263 Phosphorylation HPRD 18491316, 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1096 Y1096 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1096 A1096 Biomuta DOID:1319 / brain cancer [ icgc ]
S1164 L1164 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1225 Y1225 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1230 C1230 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1231 F1231 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1241 L1241 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1265 A1265 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1306 G1306 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1320 P1320 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1323 C1323 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1475 A1475 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1522 C1522 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1701 A1701 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1738 N1738 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1815 C1815 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1815 P1815 Biomuta DOID:363 / uterine cancer [ icgc ]
S1907 T1907 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1909 G1909 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1992 Y1992 Biomuta DOID:1319 / brain cancer [ icgc ]
S2069 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S2069 P2069 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2132 L2132 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S2231 F2231 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2263 A2263 Biomuta DOID:3571 / liver cancer [ cosmic ]