iPTMnet Report Q8WYK2 JDP2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8WYK2 / JDP2_HUMAN
Protein Name	Jun dimerization protein 2
Gene Name	Name: JDP2
Organism	Homo sapiens (Human)

PRO ID	PR:Q8WYK2 DAG View
PRO Name	Jun dimerization protein 2 (human)
Definition	A Jun dimerization protein 2 that is encoded in the genome of human.
Short Label	hJDP2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8WYK2 (JDP2) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K65	Sumoylation		score1	PhosphoSitePlus
	T116	Phosphorylation		score0	RLIMS-P	31434880
	T138	Phosphorylation		score1	PhosphoSitePlus
	T143	Phosphorylation		score1	PhosphoSitePlus
	S145	Phosphorylation		score1	PhosphoSitePlus
	T148	Phosphorylation		score4	neXtProt PhosphoSitePlus RLIMS-P UniProt	21463260, 18307971, 12225289, ...11602244, 23186163, 23530091
	T148	Phosphorylation	P45983 (MAPK8)	score2	neXtProt	11602244
	T148	Phosphorylation	P45984 (MAPK9)	score3	neXtProt PhosphoSitePlus	12225289
	T148	Phosphorylation	Q16539 (MAPK14)	score3	neXtProt PhosphoSitePlus	12225289
	S151	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T148	Phosphorylation		score2	HPRD	12225289, 11602244
	T148	Phosphorylation	P45983 (MAPK8)	score2	HPRD	12225289, 11602244
	T148	Phosphorylation	P45984 (MAPK9)	score2	HPRD	12225289, 11602244
	T148	Phosphorylation	Q16539 (MAPK14)	score2	HPRD	12225289, 11602244

PTM-dependent PPI

	PTM type	Substrate	Site	Interactant	Association type	Source	PMID
	Phosphorylation	P06401 (PGR)	S400	Q8WYK2 (JDP2)	unknown	eFIP	20008003

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T138	I138	Biomuta		DOID:3571 / liver cancer [ cosmic ]