Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WYK0 / ACO12_HUMAN
Protein Name Acetyl-coenzyme A thioesterase
Gene Name Name: ACOT12
Synonyms:CACH,CACH1,STARD15;
Organism Homo sapiens (Human)

PRO ID PR:Q8WYK0
DAG View
PRO Name acyl-coenzyme A thioesterase 12 (human)
Definition An acyl-coenzyme A thioesterase 12 that is encoded in the genome of human.
Short Label hACOT12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WYK0 (ACOT12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S82 Phosphorylation PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
Y329 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
Y485 Phosphorylation PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
T554 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S82 R82 Biomuta DOID:3571 / liver cancer [ icgc ]
T83 K83 Biomuta DOID:3571 / liver cancer [ icgc ]
S473 L473 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:3963 / thyroid carcinoma [ cosmic, tcga ]