Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WYJ6 / SEPT1_HUMAN
Protein Name Septin-1
Gene Name Name: SEPTIN1
Synonyms:DIFF6,PNUTL3,SEPT1;
Organism Homo sapiens (Human)

PRO ID PR:Q8WYJ6
DAG View
PRO Name septin-1 (human)
Definition A septin-1 that is encoded in the genome of human.
Short Label hSEPTIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WYJ6 (SEPTIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
Y5 Phosphorylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
T48 Phosphorylation PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus   UniProt 24275569
K213 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
R240 Methylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
S248 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus   RLIMS-P   UniProt 19690332, 16179162
T251 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
Y286 Phosphorylation PhosphoSitePlus
Y289 Phosphorylation PhosphoSitePlus
S307 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus   RLIMS-P   UniProt 16179162
S315 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus   RLIMS-P   UniProt 19690332, 16179162
T317 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K22 R22 Biomuta DOID:363 / uterine cancer [ tcga ]
K127 N127 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y199 F199 Biomuta DOID:1324 / lung cancer [ tcga ]
S248 Y248 Biomuta DOID:3571 / liver cancer [ icgc ]
T251 N251 Biomuta DOID:3571 / liver cancer [ icgc ]