iPTMnet Report for Q8WYH8 (ING5)
Protein Information
UniProt AC / UniProt ID | Q8WYH8 / ING5_HUMAN |
Protein Name | Inhibitor of growth protein 5 |
Gene Name | Name: ING5 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WYH8 |
PRO Name | inhibitor of growth protein 5 (human) |
Definition | An inhibitor of growth protein 5 that is encoded in the genome of human. |
Short Label | hING5 |
Category | organism-gene |
Q8WYH8 (ING5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
S57 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 25860957 | ||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
R106 | Methylation | score1 | PhosphoSitePlus | |||
K112 | Acetylation | score1 | PhosphoSitePlus | |||
K114 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S118 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983, ... | ||
S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
R126 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
K129 | Acetylation | score1 | PhosphoSitePlus | |||
K130 | Acetylation | score1 | PhosphoSitePlus | |||
K135 | Acetylation | score1 | PhosphoSitePlus | |||
T147 | Phosphorylation | score1 | PhosphoSitePlus | |||
S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
T152 | Phosphorylation | P24941 (CDK2) | score3 | PhosphoSitePlus RLIMS-P | 25860957 | |
K154 | Acetylation | score1 | PhosphoSitePlus | |||
K155 | Acetylation | score1 | PhosphoSitePlus | |||
K222 | Acetylation | score1 | PhosphoSitePlus | |||
K226 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R126 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
T152 | A152 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |