iPTMnet Report for Q8WYB5 (KAT6B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WYB5 / KAT6B_HUMAN
Protein Name Histone acetyltransferase KAT6B
Gene Name Name: KAT6B
Synonyms:KIAA0383,MORF,MOZ2,MYST4;
Organism Homo sapiens (Human)

PRO ID PR:Q8WYB5
DAG View
PRO Name histone acetyltransferase KAT6B (human)
Definition A histone acetyltransferase KAT6B that is encoded in the genome of human.
Short Label hKAT6B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WYB5 (KAT6B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K127 Ubiquitination PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
K223 Acetylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus   UniProt 23186163
S362 Phosphorylation PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
R374 Methylation PhosphoSitePlus
K379 Acetylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
K393 Acetylation PhosphoSitePlus
T402 Phosphorylation PhosphoSitePlus
K412 Acetylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
T418 Phosphorylation PhosphoSitePlus
Y419 Phosphorylation PhosphoSitePlus
K440 Acetylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
T443 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S445 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S451 Phosphorylation PhosphoSitePlus
K584 Acetylation PhosphoSitePlus
K590 Acetylation PhosphoSitePlus
K615 Acetylation PhosphoSitePlus
T640 Phosphorylation PhosphoSitePlus
T645 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus   UniProt 23186163
S652 Phosphorylation PhosphoSitePlus
T654 Phosphorylation PhosphoSitePlus
K673 Sumoylation PhosphoSitePlus
Y728 Phosphorylation PhosphoSitePlus
Y757 Phosphorylation PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
K815 Acetylation PhosphoSitePlus
Y878 Phosphorylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
S998 Phosphorylation PhosphoSitePlus
C1017 Methylation IEDB 31844290
S1027 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S1035 Phosphorylation PhosphoSitePlus
K1038 Acetylation PhosphoSitePlus   UniProt 19608861
K1042 Acetylation PhosphoSitePlus   UniProt 19608861
K1044 Acetylation PhosphoSitePlus   UniProt 19608861
Y1045 Phosphorylation PhosphoSitePlus
S1048 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S1051 Phosphorylation PhosphoSitePlus
T1055 Phosphorylation PhosphoSitePlus
T1114 Phosphorylation PhosphoSitePlus
K1115 Acetylation PhosphoSitePlus
K1245 Acetylation PhosphoSitePlus
R1265 Methylation PhosphoSitePlus
T1267 Phosphorylation PhosphoSitePlus
T1279 Phosphorylation PhosphoSitePlus
T1300 Phosphorylation PhosphoSitePlus
S1301 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation PhosphoSitePlus
S1502 Phosphorylation PhosphoSitePlus
S1571 Phosphorylation PhosphoSitePlus
S1581 Phosphorylation PhosphoSitePlus
S1761 O-Glycosylation GlyGen 28314751
S1762 O-Glycosylation GlyGen 28314751
S1763 O-Glycosylation GlyGen 28314751
S1903 Phosphorylation PhosphoSitePlus
S1924 Phosphorylation PhosphoSitePlus
S1933 Phosphorylation PhosphoSitePlus
S1947 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T402 Phosphorylation HPRD 20068231
Y757 Phosphorylation HPRD 19664994
S1027 Phosphorylation HPRD 15302935
T1915 Phosphorylation HPRD 17081983
Y2070 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S371 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S217 G217 Biomuta DOID:1324 / lung cancer [ cosmic ]
S362 F362 Biomuta DOID:4159 / skin cancer [ cosmic ]
T367 R367 Biomuta DOID:1612 / breast cancer [ cosmic ]
K412 E412 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T416 S416 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S417 T417 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S451 L451 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C1017 S1017 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1035 L1035 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1045 C1045 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1502 Y1502 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
S1502 P1502 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1761 N1761 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1924 C1924 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]