iPTMnet Report for Q8WYA1 (BMAL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WYA1 / BMAL2_HUMAN
Protein Name Basic helix-loop-helix ARNT-like protein 2
Gene Name Name: BMAL2
Synonyms:ARNTL2,BHLHE6,CLIF,MOP9,PASD9;
Organism Homo sapiens (Human)

PRO ID PR:Q8WYA1
DAG View
PRO Name basic helix-loop-helix ARNT-like protein 2 (human)
Definition A basic helix-loop-helix ARNT-like protein 2 that is encoded in the genome of human.
Short Label hBMAL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WYA1 (BMAL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
K203 Acetylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
K213 Acetylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
K304 Acetylation PhosphoSitePlus
K306 Acetylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K203 R203 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K209 N209 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S212 C212 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S245 F245 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S245 C245 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S539 L539 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]