iPTMnet Report for Q8WXX7 (AUTS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WXX7 / AUTS2_HUMAN
Protein Name Autism susceptibility gene 2 protein
Gene Name Name: AUTS2
Synonyms:KIAA0442;
Organism Homo sapiens (Human)

PRO ID PR:Q8WXX7
DAG View
PRO Name autism susceptibility gene 2 protein (human)
Definition An autism susceptibility gene 2 protein that is encoded in the genome of human.
Short Label hAUTS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WXX7 (AUTS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
R27 Methylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T119 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S505 O-Glycosylation GlyGen 29351928
S507 Phosphorylation PhosphoSitePlus
R510 Methylation PhosphoSitePlus
R576 Methylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
T799 Phosphorylation PhosphoSitePlus
S852 Phosphorylation PhosphoSitePlus
S853 Phosphorylation PhosphoSitePlus
S856 Phosphorylation PhosphoSitePlus
S898 Phosphorylation PhosphoSitePlus
S941 Phosphorylation PhosphoSitePlus
Y943 Phosphorylation PhosphoSitePlus
T946 Phosphorylation PhosphoSitePlus
S956 Phosphorylation PhosphoSitePlus
S958 Phosphorylation PhosphoSitePlus
Y971 Phosphorylation PhosphoSitePlus
S1053 Phosphorylation PhosphoSitePlus
Y1063 Phosphorylation PhosphoSitePlus
S1065 Phosphorylation PhosphoSitePlus
R1092 Methylation PhosphoSitePlus
R1103 Methylation PhosphoSitePlus
S1105 Phosphorylation PhosphoSitePlus
T1106 Phosphorylation PhosphoSitePlus
R1108 Methylation PhosphoSitePlus
R1114 Methylation PhosphoSitePlus
R1145 Methylation PhosphoSitePlus
S1198 Phosphorylation PhosphoSitePlus   UniProt 21406692
T1200 Phosphorylation PhosphoSitePlus
T1211 Phosphorylation IEDB   PhosphoSitePlus 32357974
S1218 Phosphorylation PhosphoSitePlus
S1233 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
T1238 Phosphorylation PhosphoSitePlus
S1241 Phosphorylation PhosphoSitePlus
S1250 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S941 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S50 W50 Biomuta DOID:1324 / lung cancer [ cosmic ]
T119 M119 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T119 A119 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S149 N149 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S319 F319 Biomuta DOID:1324 / lung cancer [ cosmic ]
R510 H510 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R510 P510 Biomuta DOID:1324 / lung cancer [ cosmic ]
R576 Q576 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S852 F852 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S898 L898 Biomuta DOID:1319 / brain cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S898 P898 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y971 C971 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1065 F1065 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1105 L1105 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T1106 I1106 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1145 Q1145 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T1200 N1200 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1211 I1211 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]