iPTMnet Report for Q8WXW3 (PIBF1)
Protein Information
| UniProt AC / UniProt ID | Q8WXW3 / PIBF1_HUMAN |
| Protein Name | Progesterone-induced-blocking factor 1 |
| Gene Name | Name: PIBF1 Synonyms:C13orf24,PIBF; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WXW3 |
| PRO Name | progesterone-induced-blocking factor 1 (human) |
| Definition | A progesterone-induced-blocking factor 1 that is encoded in the genome of human. |
| Short Label | hPIBF1 |
| Category | organism-gene |
Q8WXW3 (PIBF1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K84 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K216 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K376 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K434 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R441 | Methylation | score1 | PhosphoSitePlus | |||
| K452 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K461 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K463 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K490 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K494 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K532 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K571 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K589 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S592 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K596 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K602 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K639 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K652 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S697 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K698 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S700 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S703 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K708 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K721 | Acetylation | score1 | PhosphoSitePlus | |||
| K721 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K727 | Acetylation | score1 | PhosphoSitePlus | |||
| T735 | Phosphorylation | score1 | IEDB | 32387766 | ||
| K737 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S68 | F68 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
| K119 | I119 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| K205 | N205 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K318 | N318 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| R441 | G441 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K452 | N452 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
| K461 | I461 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K461 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S700 | F700 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K737 | E737 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] |
DAG View