iPTMnet Report for Q8WXU2 (DNAAF4)
Protein Information
| UniProt AC / UniProt ID | Q8WXU2 / DAAF4_HUMAN |
| Protein Name | Dynein axonemal assembly factor 4 |
| Gene Name | Name: DNAAF4 Synonyms:DYX1C1,EKN1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WXU2 |
| PRO Name | dynein axonemal assembly factor 4 (human) |
| Definition | A dynein axonemal assembly factor 4 that is encoded in the genome of human. |
| Short Label | hDNAAF4 |
| Category | organism-gene |
DAG ViewQ8WXU2 (DNAAF4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S103 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
| K127 | Acetylation | score1 | PhosphoSitePlus | |||
| Y128 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K135 | Methylation | score1 | PhosphoSitePlus | |||
| K180 | Acetylation | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C333 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S103 | C103 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S103 | Y103 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| K135 | N135 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
