iPTMnet Report for Q8WXI2 (CNKSR2)
Protein Information
| UniProt AC / UniProt ID | Q8WXI2 / CNKR2_HUMAN |
| Protein Name | Connector enhancer of kinase suppressor of ras 2 |
| Gene Name | Name: CNKSR2 Synonyms:CNK2,KIAA0902,KSR2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WXI2 |
| PRO Name | connector enhancer of kinase suppressor of ras 2 (human) |
| Definition | A connector enhancer of kinase suppressor of ras 2 that is encoded in the genome of human. |
| Short Label | hCNKSR2 |
| Category | organism-gene |
DAG ViewQ8WXI2 (CNKSR2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C195 | Methylation | score1 | IEDB | 31844290 | ||
| T292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S303 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S325 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T332 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y452 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S473 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S564 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T694 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S756 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S808 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T809 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T812 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C815 | Methylation | score1 | IEDB | 31844290 | ||
| Y821 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S908 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 19690332, 24275569 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S390 | Phosphorylation | score0 | HPRD | 15345747, 19664994 | ||
| S908 | Phosphorylation | score0 | HPRD | 19664994, 19664995 | ||
| Y913 | Phosphorylation | score0 | HPRD | 18452278 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S430 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C195 | S195 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S303 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y434 | N434 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y452 | C452 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S467 | F467 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S808 | Y808 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| C815 | Y815 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
