iPTMnet Report for Q8WXF8 (DEDD2)
Protein Information
| UniProt AC / UniProt ID | Q8WXF8 / DEDD2_HUMAN |
| Protein Name | DNA-binding death effector domain-containing protein 2 |
| Gene Name | Name: DEDD2 Synonyms:FLAME3;ORFNames:PSEC0004; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WXF8 |
| PRO Name | DNA-binding death effector domain-containing protein 2 (human) |
| Definition | A DNA-binding death effector domain-containing protein 2 that is encoded in the genome of human. |
| Short Label | hDEDD2 |
| Category | organism-gene |
DAG ViewQ8WXF8 (DEDD2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y117 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S190 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y117 | H117 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T119 | I119 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S189 | F189 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S190 | C190 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
