iPTMnet Report for Q8WXF1 (PSPC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WXF1 / PSPC1_HUMAN
Protein Name Paraspeckle component 1
Gene Name Name: PSPC1
Synonyms:PSP1;
Organism Homo sapiens (Human)

PRO ID PR:Q8WXF1
DAG View
PRO Name paraspeckle component 1 (human)
Definition A paraspeckle component 1 that is encoded in the genome of human.
Short Label hPSPC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WXF1 (PSPC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
R4 Methylation PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
T159 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K206 Acetylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
Y275 Phosphorylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
R338 Methylation PhosphoSitePlus
R373 Methylation PhosphoSitePlus
K380 Acetylation PhosphoSitePlus
R392 Methylation PhosphoSitePlus
R399 Methylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus   UniProt 20068231
T453 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus   UniProt 20068231
S477 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S481 Phosphorylation PhosphoSitePlus
T487 Phosphorylation PhosphoSitePlus
S493 O-Glycosylation GlyGen 33214551, 34229054, 35132862, ...34019948
S493 Phosphorylation PhosphoSitePlus
R507 Methylation PhosphoSitePlus   UniProt 24129315
S509 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
K519 Acetylation PhosphoSitePlus
K519 Methylation PhosphoSitePlus
R520 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T159 Phosphorylation HPRD 20068231
S164 Phosphorylation HPRD 20068231
T196 Phosphorylation HPRD 20068231
S409 Phosphorylation HPRD 20068231
S473 Phosphorylation HPRD 19664995, 20068231
S477 Phosphorylation HPRD 19664995, 20068231
S509 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S473 Y473 Biomuta DOID:363 / uterine cancer [ cosmic ]
S473 A473 Biomuta DOID:363 / uterine cancer [ cosmic ]
S477 L477 Biomuta DOID:4159 / skin cancer [ cosmic ]
K519 N519 Biomuta DOID:363 / uterine cancer [ cosmic ]
R520 C520 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R520 H520 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]