iPTMnet Report for Q8WXF0 (SRSF12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WXF0 / SRS12_HUMAN
Protein Name Serine/arginine-rich splicing factor 12
Gene Name Name: SRSF12
Synonyms:SFRS13B,SFRS19,SRRP35;
Organism Homo sapiens (Human)

PRO ID PR:Q8WXF0
DAG View
PRO Name serine/arginine-rich splicing factor 12 (human)
Definition A serine/arginine-rich splicing factor 12 that is encoded in the genome of human.
Short Label hSRSF12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WXF0 (SRSF12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y55 Phosphorylation PhosphoSitePlus
K91 Methylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
S219 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
S223 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
S227 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
T236 O-Glycosylation GlyGen 23301498, 31492838
T236 Phosphorylation PhosphoSitePlus
T240 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S122 R122 Biomuta [ cosmic ]
S124 N124 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S150 C150 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S223 P223 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S223 F223 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]