iPTMnet Report for Q8WXD9 (CASKIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WXD9 / CSKI1_HUMAN
Protein Name Caskin-1
Gene Name Name: CASKIN1
Synonyms:KIAA1306;
Organism Homo sapiens (Human)

PRO ID PR:Q8WXD9
DAG View
PRO Name caskin-1 (human)
Definition A caskin-1 that is encoded in the genome of human.
Short Label hCASKIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WXD9 (CASKIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K149 Ubiquitination PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
Y296 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P 23181695
Y296 Phosphorylation P54762 (EPHB1) neXtProt 23181695
Y336 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   RLIMS-P 18691976, 23181695
Y336 Phosphorylation P54762 (EPHB1) neXtProt 23181695
R398 Methylation PhosphoSitePlus   UniProt 24129315
S423 Phosphorylation PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
K601 Methylation PhosphoSitePlus
K607 Methylation PhosphoSitePlus
K612 Methylation PhosphoSitePlus
S646 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
T775 Phosphorylation PhosphoSitePlus
T779 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus   UniProt 23186163
S819 Phosphorylation PhosphoSitePlus
S822 Phosphorylation PhosphoSitePlus
S826 Phosphorylation PhosphoSitePlus
S919 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
S987 Phosphorylation PhosphoSitePlus
T1029 Phosphorylation PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus
S1046 Phosphorylation PhosphoSitePlus
T1065 Phosphorylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
T1071 Phosphorylation PhosphoSitePlus
T1076 Phosphorylation PhosphoSitePlus
T1123 Phosphorylation PhosphoSitePlus
T1143 O-Glycosylation GlyGen 28411811, 28657654, 29351928
S1145 O-Glycosylation GlyGen 28411811, 28657654, 29351928
S1227 Phosphorylation PhosphoSitePlus
S1242 Phosphorylation PhosphoSitePlus
S1257 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163
S1364 Phosphorylation PhosphoSitePlus
T1376 Phosphorylation PhosphoSitePlus
S1377 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R398 Q398 Biomuta DOID:4159 / skin cancer [ cosmic ]
S822 F822 Biomuta DOID:363 / uterine cancer [ icgc ]
S935 F935 Biomuta DOID:4159 / skin cancer [ cosmic ]
S987 N987 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]