iPTMnet Report for Q8WXD2 (SCG3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WXD2 / SCG3_HUMAN
Protein Name Secretogranin-3 precursor
Gene Name Name: SCG3
ORFNames:UNQ2502/PRO5990;
Organism Homo sapiens (Human)

PRO ID PR:Q8WXD2
DAG View
PRO Name secretogranin-3 (human)
Definition A secretogranin-3 that is encoded in the genome of human.
Short Label hSCG3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WXD2 (SCG3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S37 O-Glycosylation GlyGen   UniProt 25326458
S37 Phosphorylation PhosphoSitePlus
T144 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
Y208 Phosphorylation PhosphoSitePlus
T216 O-Glycosylation GlyGen   UniProt 23234360
T231 O-Glycosylation GlyGen   UniProt 23234360
K294 Ubiquitination PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
N346 N-Glycosylation GlyGen 29741879
N350 N-Glycosylation GlyGen 29741879
S359 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 23234360
S362 Phosphorylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
K397 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S37 Phosphorylation HPRD 18702456
N346 N-Glycosylation PRO 29741879
N350 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T231 N231 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S320 F320 Biomuta DOID:4159 / skin cancer [ cosmic ]
S320 Y320 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S359 L359 Biomuta DOID:4159 / skin cancer [ cosmic ]
S362 G362 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]