iPTMnet Report for Q8WX94 (NLRP7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WX94 / NALP7_HUMAN
Protein Name NACHT, LRR and PYD domains-containing protein 7
Gene Name Name: NLRP7
Synonyms:NALP7,NOD12,PYPAF3;
Organism Homo sapiens (Human)

PRO ID PR:Q8WX94
DAG View
PRO Name NACHT, LRR and PYD domains-containing protein 7 (human)
Definition A NACHT, LRR and PYD domains-containing protein 7 that is encoded in the genome of human.
Short Label hNLRP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WX94 (NLRP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
S3 Phosphorylation PhosphoSitePlus
T61 Phosphorylation PhosphoSitePlus
T81 Phosphorylation PhosphoSitePlus
K189 Acetylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
T734 Phosphorylation PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
Y810 Phosphorylation PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
K836 Acetylation PhosphoSitePlus
K847 Acetylation PhosphoSitePlus
T849 Phosphorylation PhosphoSitePlus
K855 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y318 Phosphorylation PhosphoSitePlus
T704 Phosphorylation PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
T709 Phosphorylation PhosphoSitePlus
K808 Acetylation PhosphoSitePlus
K819 Acetylation PhosphoSitePlus
K827 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T706 M706 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K808 E808 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K827 N827 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]