iPTMnet Report for Q8WWZ7 (ABCA5)
Protein Information
UniProt AC / UniProt ID | Q8WWZ7 / ABCA5_HUMAN |
Protein Name | Cholesterol transporter ABCA5 |
Gene Name | Name: ABCA5 Synonyms:KIAA1888; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WWZ7 |
PRO Name | cholesterol transporter ABCA5 (human) |
Definition | A cholesterol transporter ABCA5 that is encoded in the genome of human. |
Short Label | hABCA5 |
Category | organism-gene |
Q8WWZ7 (ABCA5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y137 | Phosphorylation | score1 | PhosphoSitePlus | |||
S155 | Phosphorylation | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
R218 | Methylation | score1 | PhosphoSitePlus | |||
K490 | Ubiquitination | score1 | PhosphoSitePlus | |||
K608 | Ubiquitination | score1 | PhosphoSitePlus | |||
K614 | Acetylation | score1 | PhosphoSitePlus | |||
S616 | Phosphorylation | score1 | PhosphoSitePlus | |||
K620 | Acetylation | score1 | PhosphoSitePlus | |||
S624 | Phosphorylation | score1 | PhosphoSitePlus | |||
T642 | Phosphorylation | score1 | PhosphoSitePlus | |||
S649 | Phosphorylation | score1 | PhosphoSitePlus | |||
K683 | Methylation | score1 | PhosphoSitePlus | |||
S687 | Phosphorylation | score1 | PhosphoSitePlus | |||
K701 | Ubiquitination | score1 | PhosphoSitePlus | |||
K703 | Ubiquitination | score1 | PhosphoSitePlus | |||
T854 | Phosphorylation | score1 | PhosphoSitePlus | |||
S859 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1050 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1254 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1299 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1405 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1407 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1410 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1423 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1428 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1562 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1564 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1565 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1569 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1585 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R218 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
R218 | L218 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K490 | N490 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K614 | N614 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S616 | R616 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
K683 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S687 | L687 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S1405 | I1405 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S1564 | C1564 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S1565 | F1565 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |