Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WWZ7 / ABCA5_HUMAN
Protein Name Cholesterol transporter ABCA5
Gene Name Name: ABCA5
Synonyms:KIAA1888;
Organism Homo sapiens (Human)

PRO ID PR:Q8WWZ7
DAG View
PRO Name cholesterol transporter ABCA5 (human)
Definition A cholesterol transporter ABCA5 that is encoded in the genome of human.
Short Label hABCA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WWZ7 (ABCA5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S134 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
R218 Methylation PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K614 Acetylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
K620 Acetylation PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus
T642 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
K683 Methylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
T854 Phosphorylation PhosphoSitePlus
S859 Phosphorylation PhosphoSitePlus
K1050 Ubiquitination PhosphoSitePlus
K1254 Ubiquitination PhosphoSitePlus
Y1299 Phosphorylation PhosphoSitePlus
S1405 Phosphorylation PhosphoSitePlus
S1407 Phosphorylation PhosphoSitePlus
K1410 Ubiquitination PhosphoSitePlus
K1423 Ubiquitination PhosphoSitePlus
K1428 Ubiquitination PhosphoSitePlus
S1562 Phosphorylation PhosphoSitePlus
S1564 Phosphorylation PhosphoSitePlus
S1565 Phosphorylation PhosphoSitePlus
Y1569 Phosphorylation PhosphoSitePlus
K1585 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S134 Phosphorylation HPRD 20166139
Y137 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R218 * Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R218 L218 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K490 N490 Biomuta DOID:1324 / lung cancer [ tcga ]
K614 N614 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S616 R616 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S687 L687 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S1405 I1405 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S1564 C1564 Biomuta DOID:1324 / lung cancer [ cosmic ]