iPTMnet Report for Q8WWN8 (ARAP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WWN8 / ARAP3_HUMAN
Protein Name Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Gene Name Name: ARAP3
Synonyms:CENTD3;
Organism Homo sapiens (Human)

PRO ID PR:Q8WWN8
DAG View
PRO Name Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (human)
Definition An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 that is encoded in the genome of human.
Short Label hARAP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WWN8 (ARAP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S132 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
C203 Methylation IEDB 31844290
Y205 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
K296 Acetylation IEDB 34357683
K296 Ubiquitination PhosphoSitePlus
Y303 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
Y670 Phosphorylation PhosphoSitePlus
Y684 Phosphorylation PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
S858 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
Y882 Phosphorylation PhosphoSitePlus
Y941 Phosphorylation PhosphoSitePlus
T977 Phosphorylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
K1009 Ubiquitination PhosphoSitePlus
Y1016 Phosphorylation PhosphoSitePlus
K1182 Ubiquitination PhosphoSitePlus
K1184 Ubiquitination PhosphoSitePlus
K1206 Ubiquitination PhosphoSitePlus
S1337 Phosphorylation PhosphoSitePlus
K1345 Ubiquitination PhosphoSitePlus
T1348 Phosphorylation PhosphoSitePlus
T1369 Phosphorylation PhosphoSitePlus
S1380 Phosphorylation PhosphoSitePlus
Y1403 Phosphorylation PhosphoSitePlus
Y1408 Phosphorylation PhosphoSitePlus
K1434 Ubiquitination PhosphoSitePlus
K1443 Ubiquitination PhosphoSitePlus
S1444 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
K1452 Ubiquitination PhosphoSitePlus
K1472 Ubiquitination PhosphoSitePlus
S1474 Phosphorylation PhosphoSitePlus
S1480 Phosphorylation PhosphoSitePlus   UniProt 21406692
S1490 Phosphorylation PhosphoSitePlus
S1491 Phosphorylation PhosphoSitePlus
S1507 Phosphorylation PhosphoSitePlus
S1511 Phosphorylation PhosphoSitePlus
S1514 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S858 Phosphorylation HPRD 20058876
S1444 Phosphorylation HPRD 18669648
S1473 Phosphorylation HPRD 19651622
S1480 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S322 N322 Biomuta DOID:4159 / skin cancer [ cosmic ]
S415 N415 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K540 N540 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y670 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S861 F861 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T979 I979 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1182 N1182 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1337 F1337 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1337 C1337 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1403 H1403 Biomuta DOID:2531 / hematologic cancer [ icgc ]
Y1403 N1403 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1473 N1473 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1474 C1474 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1491 R1491 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1507 F1507 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1507 P1507 Biomuta DOID:363 / uterine cancer [ icgc ]
S1514 P1514 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ]