iPTMnet Report for Q8WWM7 (ATXN2L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WWM7 / ATX2L_HUMAN
Protein Name Ataxin-2-like protein
Gene Name Name: ATXN2L
Synonyms:A2D,A2LG,A2LP,A2RP;
Organism Homo sapiens (Human)

PRO ID PR:Q8WWM7
DAG View
PRO Name ataxin-2-like protein (human)
Definition An ataxin-2-like protein that is encoded in the genome of human.
Short Label hATXN2L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WWM7 (ATXN2L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
T31 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S32 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S45 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
S45 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
C58 Methylation IEDB 31844290
S67 Phosphorylation PhosphoSitePlus
R71 Methylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
S103 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K106 Ubiquitination PhosphoSitePlus
S111 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 21406692, 23186163, ...16964243, 18220336, 15302935, 15144186, 18669648, 17287340, 19690332, 20068231
Y118 Phosphorylation PhosphoSitePlus   UniProt 19690332
T128 Phosphorylation PhosphoSitePlus
C135 Methylation IEDB 31844290
K138 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus   UniProt 19690332
Y241 Phosphorylation PhosphoSitePlus
Y264 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 15144186
K267 Ubiquitination PhosphoSitePlus
T268 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
T269 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
Y270 Phosphorylation PhosphoSitePlus
S272 O-Glycosylation GlyGen 31373491
S272 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S305 Phosphorylation IEDB   PhosphoSitePlus 27920218
S306 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 27920218, 18669648, 23186163
Y309 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 15144186
T322 Phosphorylation PhosphoSitePlus
S335 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17287340, 20068231
S339 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17287340, 17081983, ...20068231
S341 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340, 17081983
S344 Phosphorylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
Y349 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 15144186
R355 Methylation PhosphoSitePlus
R361 Methylation PhosphoSitePlus   UniProt 25748791
R365 Methylation PhosphoSitePlus
S369 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
R370 Methylation PhosphoSitePlus
R373 Methylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
R382 Methylation PhosphoSitePlus
S390 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S391 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 15144186
S396 Phosphorylation PhosphoSitePlus
R399 Methylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
S409 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...27869121, 20068231
R414 Methylation PhosphoSitePlus
R417 Methylation IEDB   PhosphoSitePlus 27503676
T421 O-Glycosylation GlyGen 31373491
T421 Phosphorylation PhosphoSitePlus
S423 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S424 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S426 O-Glycosylation GlyGen 31373491
S426 Phosphorylation PhosphoSitePlus
R428 Methylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
Y445 Phosphorylation PhosphoSitePlus
S449 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 18220336
S461 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
T473 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
S491 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus   UniProt 20068231
S496 O-Glycosylation GlyGen 22661428
S496 Phosphorylation IEDB   PhosphoSitePlus   UniProt 21406692, 17081983, 32157095, ...30784271, 20068231
S500 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
S500 Phosphorylation PhosphoSitePlus
T504 O-Glycosylation GlyGen 32574038
K507 Ubiquitination PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
R539 Methylation PhosphoSitePlus
R546 Methylation PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
K553 Methylation PhosphoSitePlus
K553 Ubiquitination PhosphoSitePlus
S557 O-Glycosylation GlyGen 31373491
S557 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
S558 O-Glycosylation GlyGen 31373491
S558 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 23186163, 19690332
S559 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 18220336, 15302935, ...15144186, 18669648, 23186163, 19690332, 20068231
S563 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
S563 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 17287340
K573 Sumoylation PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
S589 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340, 17081983
S594 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 21406692, 23186163, ...16964243, 15302935, 18669648, 24275569, 17287340, 19690332, 20068231, 17081983
S597 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S598 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T600 Phosphorylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T618 Phosphorylation PhosphoSitePlus
S630 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T632 Phosphorylation PhosphoSitePlus   UniProt 24275569
S634 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
K641 Sumoylation PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
T658 Phosphorylation PhosphoSitePlus
K670 Acetylation PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
S674 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
S674 Phosphorylation PhosphoSitePlus   UniProt 23186163
S678 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 34846842, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054, 20068230
S678 Phosphorylation PhosphoSitePlus
T679 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
T679 Phosphorylation PhosphoSitePlus
S680 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
S680 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T681 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
T681 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T683 O-Glycosylation GlyGen 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054
T683 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S684 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 34725712, 35138101, ...30620550, 31492838, 32870666, 29351928, 22661428, 29237092, 27114449, 31637018, 31373491, 32119511, 30397120, 32574038, 35132862, 20305658, 28657654, 33214551, 30379171, 30059200, 21740066, 35254053, 34019948, 34229054, 20068230
S684 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
R688 Methylation PhosphoSitePlus
Y706 Phosphorylation PhosphoSitePlus
Y744 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation HPRD 18669648, 20068231
S32 Phosphorylation HPRD 18669648
T44 Phosphorylation HPRD 17081983, 20068231
S45 Phosphorylation HPRD 17081983
S67 Phosphorylation HPRD 17081983
S103 Phosphorylation HPRD 18669648
S111 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 20230923, 18767875, 19664994, 19691289, 19664995, 19651622, 18669648, 20058876, 18707149, 18452278, 19415658, 20068231, 18212344
S121 Phosphorylation HPRD 20068231
T134 Phosphorylation HPRD 20068231
Y241 Phosphorylation HPRD 20068231
Y264 Phosphorylation HPRD 15144186
Y277 Phosphorylation HPRD 15592455
S306 Phosphorylation HPRD 17322306, 18669648, 19664994, ...20068231
Y309 Phosphorylation HPRD 15144186
S335 Phosphorylation HPRD 18767875, 17287340, 17081983, ...20068231
S339 Phosphorylation HPRD 17322306, 18691976, 17287340, ...20068231
S341 Phosphorylation HPRD 17287340, 17081983, 20068231
S344 Phosphorylation HPRD 17081983
Y349 Phosphorylation HPRD 15144186
S378 Phosphorylation HPRD 18767875
S390 Phosphorylation HPRD 17322306, 18669648, 20068231, ...17924679
S391 Phosphorylation HPRD 15144186, 20068231, 17924679
S406 Phosphorylation HPRD 20068231
S409 Phosphorylation HPRD 17081983, 20068231, 18212344
S423 Phosphorylation HPRD 18669648
S424 Phosphorylation HPRD 18669648, 20068231
S449 Phosphorylation HPRD 17322306, 18767875, 19651622, ...18212344, 20068231
S491 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 17081983, 20068231
S496 Phosphorylation HPRD 19413330, 17081983, 20068231, ...19664995
S557 Phosphorylation HPRD 18669648, 17287340, 19664995, ...20068231
S558 Phosphorylation HPRD 17287340, 19664995, 20068231
S559 Phosphorylation HPRD 19413330, 17287340, 19664994, ...19664995, 18452278, 17322306, 18669648, 20068231, 17924679
S563 Phosphorylation HPRD 18669648, 17287340, 20230923
T588 Phosphorylation HPRD 20068231
S589 Phosphorylation HPRD 18452278, 19415658, 20068231, ...17081983
S594 Phosphorylation HPRD 19413330, 18691976, 17287340, ...16964243, 20230923, 18767875, 19664994, 19651622, 18452278, 17322306, 18669648, 20058876, 18707149, 19415658, 20068231
S597 Phosphorylation HPRD 19413330, 20068231, 20230923
S598 Phosphorylation HPRD 19413330, 20068231
S615 Phosphorylation HPRD 17081983
T632 Phosphorylation HPRD 20068231
S634 Phosphorylation HPRD 18669648, 17081983, 18452278
S680 Phosphorylation HPRD 18669648
T681 Phosphorylation HPRD 18669648
T683 Phosphorylation HPRD 18669648, 19664995, 20068231
S684 Phosphorylation HPRD 19651622, 18669648, 17924679, ...19691289, 18212344
Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation HPRD 18669648, 20068231
S32 Phosphorylation HPRD 18669648
T44 Phosphorylation HPRD 17081983, 20068231
S45 Phosphorylation HPRD 17081983
S67 Phosphorylation HPRD 17081983
S103 Phosphorylation HPRD 18669648
S111 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 20230923, 18767875, 19664994, 19691289, 19664995, 19651622, 18669648, 20058876, 18707149, 18452278, 19415658, 20068231, 18212344
S121 Phosphorylation HPRD 20068231
T134 Phosphorylation HPRD 20068231
Y241 Phosphorylation HPRD 20068231
Y264 Phosphorylation HPRD 15144186
Y277 Phosphorylation HPRD 15592455
S306 Phosphorylation HPRD 17322306, 18669648, 19664994, ...20068231
Y309 Phosphorylation HPRD 15144186
S335 Phosphorylation HPRD 18767875, 17287340, 17081983, ...20068231
S339 Phosphorylation HPRD 17322306, 18691976, 17287340, ...20068231
S341 Phosphorylation HPRD 17287340, 17081983, 20068231
S344 Phosphorylation HPRD 17081983
Y349 Phosphorylation HPRD 15144186
S378 Phosphorylation HPRD 18767875
S390 Phosphorylation HPRD 17322306, 18669648, 20068231, ...17924679
S391 Phosphorylation HPRD 15144186, 20068231, 17924679
S406 Phosphorylation HPRD 20068231
S409 Phosphorylation HPRD 17081983, 20068231, 18212344
S423 Phosphorylation HPRD 18669648
S424 Phosphorylation HPRD 18669648, 20068231
S449 Phosphorylation HPRD 17322306, 18767875, 19651622, ...18212344, 20068231
S491 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 17081983, 20068231
S496 Phosphorylation HPRD 19413330, 17081983, 20068231, ...19664995
S557 Phosphorylation HPRD 18669648, 17287340, 19664995, ...20068231
S558 Phosphorylation HPRD 17287340, 19664995, 20068231
S559 Phosphorylation HPRD 19413330, 17287340, 19664994, ...19664995, 18452278, 17322306, 18669648, 20068231, 17924679
S563 Phosphorylation HPRD 18669648, 17287340, 20230923
T588 Phosphorylation HPRD 20068231
S589 Phosphorylation HPRD 18452278, 19415658, 20068231, ...17081983
S594 Phosphorylation HPRD 19413330, 18691976, 17287340, ...16964243, 20230923, 18767875, 19664994, 19651622, 18452278, 17322306, 18669648, 20058876, 18707149, 19415658, 20068231
S597 Phosphorylation HPRD 19413330, 20068231, 20230923
S598 Phosphorylation HPRD 19413330, 20068231
S615 Phosphorylation HPRD 17081983
T632 Phosphorylation HPRD 20068231
S634 Phosphorylation HPRD 18669648, 17081983, 18452278
S680 Phosphorylation HPRD 18669648
T681 Phosphorylation HPRD 18669648
T683 Phosphorylation HPRD 18669648, 19664995, 20068231
S684 Phosphorylation HPRD 19651622, 18669648, 17924679, ...19691289, 18212344
Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation HPRD 18669648, 20068231
S32 Phosphorylation HPRD 18669648
T44 Phosphorylation HPRD 17081983, 20068231
S45 Phosphorylation HPRD 17081983
S67 Phosphorylation HPRD 17081983
S103 Phosphorylation HPRD 18669648
S111 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 20230923, 18767875, 19664994, 19691289, 19664995, 19651622, 18669648, 20058876, 18707149, 18452278, 19415658, 20068231, 18212344
S121 Phosphorylation HPRD 20068231
T134 Phosphorylation HPRD 20068231
Y241 Phosphorylation HPRD 20068231
Y264 Phosphorylation HPRD 15144186
Y277 Phosphorylation HPRD 15592455
S306 Phosphorylation HPRD 17322306, 18669648, 19664994, ...20068231
Y309 Phosphorylation HPRD 15144186
S335 Phosphorylation HPRD 18767875, 17287340, 17081983, ...20068231
S339 Phosphorylation HPRD 17322306, 18691976, 17287340, ...20068231
S341 Phosphorylation HPRD 17287340, 17081983, 20068231
S344 Phosphorylation HPRD 17081983
Y349 Phosphorylation HPRD 15144186
S378 Phosphorylation HPRD 18767875
S390 Phosphorylation HPRD 17322306, 18669648, 20068231, ...17924679
S391 Phosphorylation HPRD 15144186, 20068231, 17924679
S406 Phosphorylation HPRD 20068231
S409 Phosphorylation HPRD 17081983, 20068231, 18212344
S423 Phosphorylation HPRD 18669648
S424 Phosphorylation HPRD 18669648, 20068231
S449 Phosphorylation HPRD 17322306, 18767875, 19651622, ...18212344, 20068231
S491 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 17081983, 20068231
S496 Phosphorylation HPRD 19413330, 17081983, 20068231, ...19664995
S557 Phosphorylation HPRD 18669648, 17287340, 19664995, ...20068231
S558 Phosphorylation HPRD 17287340, 19664995, 20068231
S559 Phosphorylation HPRD 19413330, 17287340, 19664994, ...19664995, 18452278, 17322306, 18669648, 20068231, 17924679
S563 Phosphorylation HPRD 18669648, 17287340, 20230923
T588 Phosphorylation HPRD 20068231
S589 Phosphorylation HPRD 18452278, 19415658, 20068231, ...17081983
S594 Phosphorylation HPRD 19413330, 18691976, 17287340, ...16964243, 20230923, 18767875, 19664994, 19651622, 18452278, 17322306, 18669648, 20058876, 18707149, 19415658, 20068231
S597 Phosphorylation HPRD 19413330, 20068231, 20230923
S598 Phosphorylation HPRD 19413330, 20068231
S615 Phosphorylation HPRD 17081983
T632 Phosphorylation HPRD 20068231
S634 Phosphorylation HPRD 18669648, 17081983, 18452278
S680 Phosphorylation HPRD 18669648
T681 Phosphorylation HPRD 18669648
T683 Phosphorylation HPRD 18669648, 19664995, 20068231
S684 Phosphorylation HPRD 19651622, 18669648, 17924679, ...19691289, 18212344
Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation HPRD 18669648, 20068231
S32 Phosphorylation HPRD 18669648
T44 Phosphorylation HPRD 17081983, 20068231
S45 Phosphorylation HPRD 17081983
S67 Phosphorylation HPRD 17081983
S103 Phosphorylation HPRD 18669648
S111 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 20230923, 18767875, 19664994, 19691289, 19664995, 19651622, 18669648, 20058876, 18707149, 18452278, 19415658, 20068231, 18212344
S121 Phosphorylation HPRD 20068231
T134 Phosphorylation HPRD 20068231
Y241 Phosphorylation HPRD 20068231
Y264 Phosphorylation HPRD 15144186
Y277 Phosphorylation HPRD 15592455
S306 Phosphorylation HPRD 17322306, 18669648, 19664994, ...20068231
Y309 Phosphorylation HPRD 15144186
S335 Phosphorylation HPRD 18767875, 17287340, 17081983, ...20068231
S339 Phosphorylation HPRD 17322306, 18691976, 17287340, ...20068231
S341 Phosphorylation HPRD 17287340, 17081983, 20068231
S344 Phosphorylation HPRD 17081983
Y349 Phosphorylation HPRD 15144186
S378 Phosphorylation HPRD 18767875
S390 Phosphorylation HPRD 17322306, 18669648, 20068231, ...17924679
S391 Phosphorylation HPRD 15144186, 20068231, 17924679
S406 Phosphorylation HPRD 20068231
S409 Phosphorylation HPRD 17081983, 20068231, 18212344
S423 Phosphorylation HPRD 18669648
S424 Phosphorylation HPRD 18669648, 20068231
S449 Phosphorylation HPRD 17322306, 18767875, 19651622, ...18212344, 20068231
S491 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 17081983, 20068231
S496 Phosphorylation HPRD 19413330, 17081983, 20068231, ...19664995
S557 Phosphorylation HPRD 18669648, 17287340, 19664995, ...20068231
S558 Phosphorylation HPRD 17287340, 19664995, 20068231
S559 Phosphorylation HPRD 19413330, 17287340, 19664994, ...19664995, 18452278, 17322306, 18669648, 20068231, 17924679
S563 Phosphorylation HPRD 18669648, 17287340, 20230923
T588 Phosphorylation HPRD 20068231
S589 Phosphorylation HPRD 18452278, 19415658, 20068231, ...17081983
S594 Phosphorylation HPRD 19413330, 18691976, 17287340, ...16964243, 20230923, 18767875, 19664994, 19651622, 18452278, 17322306, 18669648, 20058876, 18707149, 19415658, 20068231
S597 Phosphorylation HPRD 19413330, 20068231, 20230923
S598 Phosphorylation HPRD 19413330, 20068231
S615 Phosphorylation HPRD 17081983
T632 Phosphorylation HPRD 20068231
S634 Phosphorylation HPRD 18669648, 17081983, 18452278
S680 Phosphorylation HPRD 18669648
T681 Phosphorylation HPRD 18669648
T683 Phosphorylation HPRD 18669648, 19664995, 20068231
S684 Phosphorylation HPRD 19651622, 18669648, 17924679, ...19691289, 18212344
Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation HPRD 18669648, 20068231
S32 Phosphorylation HPRD 18669648
T44 Phosphorylation HPRD 17081983, 20068231
S45 Phosphorylation HPRD 17081983
S67 Phosphorylation HPRD 17081983
S103 Phosphorylation HPRD 18669648
S111 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 20230923, 18767875, 19664994, 19691289, 19664995, 19651622, 18669648, 20058876, 18707149, 18452278, 19415658, 20068231, 18212344
S121 Phosphorylation HPRD 20068231
T134 Phosphorylation HPRD 20068231
Y241 Phosphorylation HPRD 20068231
Y264 Phosphorylation HPRD 15144186
Y277 Phosphorylation HPRD 15592455
S306 Phosphorylation HPRD 17322306, 18669648, 19664994, ...20068231
Y309 Phosphorylation HPRD 15144186
S335 Phosphorylation HPRD 18767875, 17287340, 17081983, ...20068231
S339 Phosphorylation HPRD 17322306, 18691976, 17287340, ...20068231
S341 Phosphorylation HPRD 17287340, 17081983, 20068231
S344 Phosphorylation HPRD 17081983
Y349 Phosphorylation HPRD 15144186
S378 Phosphorylation HPRD 18767875
S390 Phosphorylation HPRD 17322306, 18669648, 20068231, ...17924679
S391 Phosphorylation HPRD 15144186, 20068231, 17924679
S406 Phosphorylation HPRD 20068231
S409 Phosphorylation HPRD 17081983, 20068231, 18212344
S423 Phosphorylation HPRD 18669648
S424 Phosphorylation HPRD 18669648, 20068231
S449 Phosphorylation HPRD 17322306, 18767875, 19651622, ...18212344, 20068231
S491 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 17081983, 20068231
S496 Phosphorylation HPRD 19413330, 17081983, 20068231, ...19664995
S557 Phosphorylation HPRD 18669648, 17287340, 19664995, ...20068231
S558 Phosphorylation HPRD 17287340, 19664995, 20068231
S559 Phosphorylation HPRD 19413330, 17287340, 19664994, ...19664995, 18452278, 17322306, 18669648, 20068231, 17924679
S563 Phosphorylation HPRD 18669648, 17287340, 20230923
T588 Phosphorylation HPRD 20068231
S589 Phosphorylation HPRD 18452278, 19415658, 20068231, ...17081983
S594 Phosphorylation HPRD 19413330, 18691976, 17287340, ...16964243, 20230923, 18767875, 19664994, 19651622, 18452278, 17322306, 18669648, 20058876, 18707149, 19415658, 20068231
S597 Phosphorylation HPRD 19413330, 20068231, 20230923
S598 Phosphorylation HPRD 19413330, 20068231
S615 Phosphorylation HPRD 17081983
T632 Phosphorylation HPRD 20068231
S634 Phosphorylation HPRD 18669648, 17081983, 18452278
S680 Phosphorylation HPRD 18669648
T681 Phosphorylation HPRD 18669648
T683 Phosphorylation HPRD 18669648, 19664995, 20068231
S684 Phosphorylation HPRD 19651622, 18669648, 17924679, ...19691289, 18212344


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T31 A31 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S103 N103 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ icgc ]
S103 G103 Biomuta DOID:363 / uterine cancer [ icgc ]
T134 I134 Biomuta DOID:4159 / skin cancer [ cosmic ]
K138 N138 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S211 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S211 L211 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S305 * Biomuta DOID:263 / kidney cancer [ cosmic ]
Y309 C309 Biomuta DOID:3571 / liver cancer [ cosmic ]
T322 S322 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T322 I322 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
Y349 C349 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R355 Q355 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R361 W361 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R365 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R365 G365 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S369 A369 Biomuta DOID:4159 / skin cancer [ icgc ]
S369 F369 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R370 W370 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R373 W373 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S378 F378 Biomuta DOID:4159 / skin cancer [ cosmic ]
R382 C382 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R382 H382 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R399 C399 Biomuta DOID:4159 / skin cancer [ cosmic ]
S406 Y406 Biomuta DOID:3571 / liver cancer [ cosmic ]
S406 C406 Biomuta DOID:1612 / breast cancer [ cosmic ]
S406 F406 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S409 Y409 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S424 L424 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S426 I426 Biomuta DOID:1324 / lung cancer [ cosmic ]
S449 F449 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S461 F461 Biomuta DOID:4159 / skin cancer [ cosmic ]
S491 Y491 Biomuta DOID:3571 / liver cancer [ cosmic ]
S496 F496 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
S500 F500 Biomuta DOID:4159 / skin cancer [ cosmic ]
R539 * Biomuta DOID:4159 / skin cancer [ cosmic ]
R539 L539 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K547 T547 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S558 I558 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S559 F559 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
S589 L589 Biomuta DOID:1612 / breast cancer [ cosmic ]
S589 T589 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S598 F598 Biomuta DOID:363 / uterine cancer [ icgc ]
T600 K600 Biomuta DOID:263 / kidney cancer [ cosmic ]
S604 L604 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S630 R630 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T683 A683 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R688 Q688 Biomuta DOID:1612 / breast cancer [ cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic ] DOID:3571 / liver cancer [ cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic ] DOID:1324 / lung cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc ] DOID:363 / uterine cancer [ icgc, icgc, icgc, icgc, icgc, icgc, icgc, icgc, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic ] DOID:4159 / skin cancer [ cosmic, cosmic, cosmic, icgc, cosmic, cosmic, icgc, cosmic, cosmic, cosmic, icgc, cosmic, cosmic, icgc, cosmic, cosmic, cosmic, icgc, cosmic, cosmic, icgc, cosmic, cosmic, cosmic, icgc, cosmic, cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic, cosmic ] DOID:1319 / brain cancer [ icgc, icgc, icgc, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc ]