Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WWK9 / CKAP2_HUMAN
Protein Name Cytoskeleton-associated protein 2
Gene Name Name: CKAP2
Synonyms:LB1;
Organism Homo sapiens (Human)

PRO ID PR:Q8WWK9
DAG View
PRO Name cytoskeleton-associated protein 2 (human)
Definition A cytoskeleton-associated protein 2 that is encoded in the genome of human.
Short Label hCKAP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WWK9 (CKAP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T3 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
T127 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
T160 Phosphorylation PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus   UniProt 23186163
K187 Ubiquitination PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus   UniProt 23186163
K198 Sumoylation PhosphoSitePlus
K206 Acetylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
S534 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 16565220
K552 Ubiquitination PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
T579 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16565220
T582 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16565220
S587 Phosphorylation PhosphoSitePlus
Y592 Phosphorylation PhosphoSitePlus
S595 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T596 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16565220
T597 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231, ...16565220
Y599 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S602 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231, ...16565220
K604 Methylation PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K605 Methylation PhosphoSitePlus
K606 Methylation PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
T612 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S614 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K617 Ubiquitination PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
T623 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 19369249, 16565220
S628 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus   Signor 20458174
K637 Ubiquitination PhosphoSitePlus
Y646 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
Y677 Phosphorylation PhosphoSitePlus
T683 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20068231
T3 Phosphorylation HPRD 20068231
S15 Phosphorylation HPRD 20068231
S61 Phosphorylation HPRD 19691289
T69 Phosphorylation HPRD 19007248
S209 Phosphorylation HPRD 19007248, 20068231, 19691289
T211 Phosphorylation HPRD 19007248
S276 Phosphorylation HPRD 19007248
T280 Phosphorylation HPRD 19007248
S304 Phosphorylation HPRD 19007248
S305 Phosphorylation HPRD 19007248
S320 Phosphorylation HPRD 20068231
S328 Phosphorylation HPRD 19007248, 19691289
S534 Phosphorylation HPRD 19007248, 20068231, 19691289
T574 Phosphorylation HPRD 19691289
T579 Phosphorylation HPRD 18669648, 19691289
T582 Phosphorylation HPRD 18669648
Y592 Phosphorylation HPRD 20068231
S595 Phosphorylation HPRD 18669648, 20068231
T596 Phosphorylation HPRD 18669648
T597 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
Y599 Phosphorylation HPRD 18669648, 20068231
S602 Phosphorylation HPRD 18669648, 19691289, 20068231
T612 Phosphorylation HPRD 18669648
S614 Phosphorylation HPRD 18669648, 17924679, 19691289, ...19007248
Site PTM Type PTM Enzyme Score Source PMID
K44 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20068231
T3 Phosphorylation HPRD 20068231
S15 Phosphorylation HPRD 20068231
K44 Ubiquitination PhosphoSitePlus
S60 Phosphorylation HPRD 19691289
T68 Phosphorylation HPRD 19007248
S208 Phosphorylation HPRD 19007248, 20068231, 19691289
T210 Phosphorylation HPRD 19007248
S275 Phosphorylation HPRD 19007248
T279 Phosphorylation HPRD 19007248
S303 Phosphorylation HPRD 19007248
S304 Phosphorylation HPRD 19007248
S319 Phosphorylation HPRD 20068231
S327 Phosphorylation HPRD 19007248, 19691289
S533 Phosphorylation HPRD 19007248, 20068231, 19691289
T573 Phosphorylation HPRD 19691289
T578 Phosphorylation HPRD 18669648, 19691289
T581 Phosphorylation HPRD 18669648
Y591 Phosphorylation HPRD 20068231
S594 Phosphorylation HPRD 18669648, 20068231
T595 Phosphorylation HPRD 18669648
T596 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
Y598 Phosphorylation HPRD 18669648, 20068231
S601 Phosphorylation HPRD 18669648, 19691289, 20068231
T611 Phosphorylation HPRD 18669648
S613 Phosphorylation HPRD 18669648, 17924679, 19691289, ...19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K70 T70 Biomuta DOID:363 / uterine cancer [ tcga ]
S124 R124 Biomuta DOID:363 / uterine cancer [ tcga ]
S139 G139 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
K206 N206 Biomuta DOID:363 / uterine cancer [ tcga ]
T280 K280 Biomuta DOID:0070003 / blastoma [ cosmic ]
K294 Q294 Biomuta DOID:3070 / malignant glioma [ tcga ]
S304 Y304 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K452 T452 Biomuta DOID:1909 / melanoma [ cosmic ]
S587 I587 Biomuta DOID:3571 / liver cancer [ icgc ]