iPTMnet Report for Q8WWA1 (TMEM40)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WWA1 / TMM40_HUMAN
Protein Name Transmembrane protein 40
Gene Name Name: TMEM40
Organism Homo sapiens (Human)

PRO ID PR:Q8WWA1
DAG View
PRO Name transmembrane protein 40 (human)
Definition A transmembrane protein 40 that is encoded in the genome of human.
Short Label hTMEM40
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WWA1 (TMEM40) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 12665801
S51 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus   UniProt 19367720
S141 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S137 Phosphorylation HPRD 20166139
S212 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S55 F55 Biomuta DOID:4159 / skin cancer [ cosmic ]
S59 L59 Biomuta DOID:4159 / skin cancer [ cosmic ]
S62 L62 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S64 P64 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S137 F137 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]