iPTMnet Report for Q8WW43 (APH1B)
Protein Information
| UniProt AC / UniProt ID | Q8WW43 / APH1B_HUMAN |
| Protein Name | Gamma-secretase subunit APH-1B |
| Gene Name | Name: APH1B Synonyms:PSFL;ORFNames:UNQ688/PRO1328; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WW43 |
| PRO Name | gamma-secretase subunit APH-1B (human) |
| Definition | A gamma-secretase subunit APH-1B that is encoded in the genome of human. |
| Short Label | hAPH1B |
| Category | organism-gene |
DAG ViewQ8WW43 (APH1B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C244 | Methylation | score1 | IEDB | 31844290 | ||
| K247 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K92 | T92 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K247 | N247 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |
