iPTMnet Report for Q8WVZ9 (KBTBD7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WVZ9 / KBTB7_HUMAN
Protein Name Kelch repeat and BTB domain-containing protein 7
Gene Name Name: KBTBD7
Organism Homo sapiens (Human)

PRO ID PR:Q8WVZ9
DAG View
PRO Name kelch repeat and BTB domain-containing protein 7 (human)
Definition A kelch repeat and BTB domain-containing protein 7 that is encoded in the genome of human.
Short Label hKBTBD7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WVZ9 (KBTBD7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus   UniProt 23186163
K54 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 Y3 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S3 F3 Biomuta DOID:4159 / skin cancer [ cosmic ]
S29 L29 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ]
K263 R263 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K288 N288 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
Y290 C290 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]