Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WVX9 / FACR1_HUMAN
Protein Name Fatty acyl-CoA reductase 1
Gene Name Name: FAR1
Synonyms:MLSTD2;ORFNames:UNQ2423/PRO4981;
Organism Homo sapiens (Human)

PRO ID PR:Q8WVX9
DAG View
PRO Name fatty acyl-CoA reductase 1 (human)
Definition A fatty acyl-CoA reductase 1 that is encoded in the genome of human.
Short Label hFAR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WVX9 (FAR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y7 Phosphorylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
K29 Sumoylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
T132 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
T371 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y7 * Biomuta DOID:363 / uterine cancer [ tcga ]
K78 I78 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T132 M132 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K176 T176 Biomuta DOID:363 / uterine cancer [ tcga ]
K443 M443 Biomuta DOID:5041 / esophageal cancer [ tcga ]