iPTMnet Report for Q8WVX9 (FAR1)
Protein Information
UniProt AC / UniProt ID | Q8WVX9 / FACR1_HUMAN |
Protein Name | Fatty acyl-CoA reductase 1 |
Gene Name | Name: FAR1 Synonyms:MLSTD2;ORFNames:UNQ2423/PRO4981; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WVX9 |
PRO Name | fatty acyl-CoA reductase 1 (human) |
Definition | A fatty acyl-CoA reductase 1 that is encoded in the genome of human. |
Short Label | hFAR1 |
Category | organism-gene |
Q8WVX9 (FAR1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y7 | Phosphorylation | score1 | PhosphoSitePlus | |||
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
K29 | Sumoylation | score1 | PhosphoSitePlus | |||
K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
S84 | Phosphorylation | score1 | PhosphoSitePlus | |||
T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
T132 | Phosphorylation | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
T371 | Phosphorylation | score1 | PhosphoSitePlus | |||
S374 | Phosphorylation | score1 | PhosphoSitePlus | |||
K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
K443 | Ubiquitination | score1 | PhosphoSitePlus | |||
S510 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K11 | N11 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
K63 | N63 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K78 | I78 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T132 | M132 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K176 | T176 | Biomuta | DOID:363 / uterine cancer [ icgc ] |