iPTMnet Report for Q8WVT3 (TRAPPC12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WVT3 / TPC12_HUMAN
Protein Name Trafficking protein particle complex subunit 12
Gene Name Name: TRAPPC12
Synonyms:TRAMM;ORFNames:CGI-87;
Organism Homo sapiens (Human)

PRO ID PR:Q8WVT3
DAG View
PRO Name trafficking protein particle complex subunit 12 (human)
Definition A trafficking protein particle complex subunit 12 that is encoded in the genome of human.
Short Label hTRAPPC12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WVT3 (TRAPPC12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S78 Phosphorylation PhosphoSitePlus
T107 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S109 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S111 Phosphorylation PhosphoSitePlus
S127 Phosphorylation HPRD   phospho.ELM 18669648
K181 Ubiquitination PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
S184 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...18669648, 20166139, 19690332
S276 Phosphorylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
K505 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
Y574 Phosphorylation PhosphoSitePlus
Y575 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
T598 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
K712 Ubiquitination PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
K733 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S184 G184 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S276 L276 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S474 F474 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y574 C574 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]