iPTMnet Report for Q8WVM7 (STAG1)
Protein Information
| UniProt AC / UniProt ID | Q8WVM7 / STAG1_HUMAN |
| Protein Name | Cohesin subunit SA-1 |
| Gene Name | Name: STAG1 Synonyms:SA1,SCC3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WVM7 |
| PRO Name | cohesin subunit SA-1 (human) |
| Definition | A cohesin subunit SA-1 that is encoded in the genome of human. |
| Short Label | hSTAG1 |
| Category | organism-gene |
Q8WVM7 (STAG1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S24 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| T46 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 22067460 | ||
| R65 | Methylation | score1 | PhosphoSitePlus | |||
| T152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T165 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K333 | Methylation | score1 | PhosphoSitePlus | |||
| K366 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T568 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T574 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K618 | Methylation | score1 | PhosphoSitePlus | |||
| K621 | Acetylation | score1 | PhosphoSitePlus | |||
| Y689 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T694 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S700 | O-Glycosylation | score1 | GlyGen | 30059200 | ||
| S756 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S758 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K759 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S781 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S847 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 22067460 | ||
| K864 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y893 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y896 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y897 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y900 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K905 | Acetylation | score1 | PhosphoSitePlus | |||
| K905 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K916 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T962 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1025 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1051 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1054 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1062 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| S1065 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S1067 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S1068 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S1070 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S1093 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T1108 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 22067460 | ||
| S1126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1138 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 22067460 | ||
| S1142 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 22067460 | ||
| T1171 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1251 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y689 | Phosphorylation | score0 | HPRD | 18452278 | ||
| T694 | Phosphorylation | score0 | HPRD | 18452278 | ||
| T962 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1062 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S1065 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S1067 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S1068 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S1070 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T1072 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1073 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1074 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T46 | S46 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T152 | N152 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| S159 | N159 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S700 | Y700 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S756 | F756 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S756 | C756 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K905 | N905 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T1054 | I1054 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| S1067 | I1067 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
DAG View