Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WVK7 / SKA2_HUMAN
Protein Name Spindle and kinetochore-associated protein 2
Gene Name Name: SKA2
Synonyms:FAM33A;
Organism Homo sapiens (Human)

PRO ID PR:Q8WVK7
DAG View
PRO Name spindle and kinetochore-associated protein 2 (human)
Definition A spindle and kinetochore-associated protein 2 that is encoded in the genome of human.
Short Label hSKA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WVK7 (SKA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K31 Ubiquitination PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163
T104 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S101 Phosphorylation HPRD 19413330, 18691976, 19007248
Site PTM Type PTM Enzyme Score Source PMID
S62 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K31 R31 Biomuta DOID:1324 / lung cancer [ cosmic ]
K41 N41 Biomuta DOID:363 / uterine cancer [ tcga ]
K41 T41 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K41 R41 Biomuta DOID:1909 / melanoma [ cosmic ]
K94 E94 Biomuta DOID:363 / uterine cancer [ tcga ]
K115 R115 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]