iPTMnet Report for Q8WVK7 (SKA2)
Protein Information
UniProt AC / UniProt ID | Q8WVK7 / SKA2_HUMAN |
Protein Name | Spindle and kinetochore-associated protein 2 |
Gene Name | Name: SKA2 Synonyms:FAM33A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WVK7 |
PRO Name | spindle and kinetochore-associated protein 2 (human) |
Definition | A spindle and kinetochore-associated protein 2 that is encoded in the genome of human. |
Short Label | hSKA2 |
Category | organism-gene |
Q8WVK7 (SKA2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
S101 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 23186163 | ||
T104 | Phosphorylation | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S101 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 19007248 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S62 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K31 | R31 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K41 | T41 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K41 | N41 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K41 | R41 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K115 | R115 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |