iPTMnet Report for Q8WVJ2 (NUDCD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WVJ2 / NUDC2_HUMAN
Protein Name NudC domain-containing protein 2
Gene Name Name: NUDCD2
Organism Homo sapiens (Human)

PRO ID PR:Q8WVJ2
DAG View
PRO Name NudC domain-containing protein 2 (human)
Definition A NudC domain-containing protein 2 that is encoded in the genome of human.
Short Label hNUDCD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WVJ2 (NUDCD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 Phosphorylation PhosphoSitePlus
C45 S-Nitrosylation dbSNO 26338901
S55 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S142 O-Glycosylation GlyGen 33214551, 28510447, 34019948, ...22661428, 35254053
S142 Phosphorylation PhosphoSitePlus   UniProt 23186163
N144 N-Glycosylation GlyGen 24190977
Y145 Phosphorylation PhosphoSitePlus
T146 O-Glycosylation GlyGen 33214551, 28510447, 34019948, ...22661428, 35254053
T146 Phosphorylation PhosphoSitePlus
K147 Sumoylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 L2 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S2 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C45 S45 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S55 L55 Biomuta DOID:1324 / lung cancer [ cosmic ]
N144 Y144 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]