iPTMnet Report for Q8WVB6 (CHTF18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WVB6 / CTF18_HUMAN
Protein Name Chromosome transmission fidelity protein 18 homolog
Gene Name Name: CHTF18
Synonyms:C16orf41,CTF18;
Organism Homo sapiens (Human)

PRO ID PR:Q8WVB6
DAG View
PRO Name chromosome transmission fidelity protein 18 homolog (human)
Definition A chromosome transmission fidelity protein 18 that is encoded in the genome of human.
Short Label hCHTF18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WVB6 (CHTF18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus   UniProt 23186163
S63 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus   UniProt 23186163, 16964243, 19690332
S70 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus 18077418
S74 Phosphorylation Q13535 (ATR) PhosphoSitePlus 18077418
S92 Phosphorylation PhosphoSitePlus
K108 Acetylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
K244 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
T382 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
T575 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
K841 Ubiquitination PhosphoSitePlus
K852 Ubiquitination PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 19690332, 20068231
K885 Ubiquitination PhosphoSitePlus
S968 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T51 Phosphorylation HPRD 19691289
S63 Phosphorylation HPRD 19413330, 18691976, 18669648, ...19664995
S64 Phosphorylation HPRD 19413330, 16964243, 18077418, ...19664995, 19691289, 18669648, 20068231
S70 Phosphorylation HPRD 18669648, 19664995, 20068231
S73 Phosphorylation HPRD 19413330, 19664995, 20068231
S74 Phosphorylation HPRD 19413330, 18077418, 17525332, ...16964243
S222 Phosphorylation HPRD 20068231
S225 Phosphorylation HPRD 18669648, 20068231
T381 Phosphorylation HPRD 20068231
T382 Phosphorylation HPRD 20068231
T575 Phosphorylation HPRD 20068231
S742 Phosphorylation HPRD 18491316
S865 Phosphorylation HPRD 18669648
S871 Phosphorylation HPRD 18691976, 20058876, 16964243, ...15302935, 19664994, 19664995, 18452278, 19651622, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S117 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S63 F63 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ icgc ]
K244 R244 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
K834 Q834 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]