Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WV93 / AFG1L_HUMAN
Protein Name AFG1-like ATPase
Gene Name Name: AFG1L
Synonyms:AFG1,LACE1;
Organism Homo sapiens (Human)

PRO ID PR:Q8WV93
DAG View
PRO Name AFG1-like ATPase (human)
Definition An AFG1-like ATPase that is encoded in the genome of human.
Short Label hAFG1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WV93 (AFG1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y133 Phosphorylation PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
Y296 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y135 F135 Biomuta DOID:3571 / liver cancer [ icgc ]
Y152 F152 Biomuta DOID:2531 / hematologic cancer [ tcga ]
K156 T156 Biomuta DOID:1324 / lung cancer [ cosmic ]
S180 I180 Biomuta DOID:3571 / liver cancer [ icgc ]