iPTMnet Report for Q8WV24 (PHLDA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WV24 / PHLA1_HUMAN
Protein Name Pleckstrin homology-like domain family A member 1
Gene Name Name: PHLDA1
Synonyms:PHRIP,TDAG51;
Organism Homo sapiens (Human)

PRO ID PR:Q8WV24
DAG View
PRO Name pleckstrin homology-like domain family A member 1 (human)
Definition A pleckstrin homology-like domain family A member 1 that is encoded in the genome of human.
Short Label hPHLDA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WV24 (PHLDA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S95 Phosphorylation O14965 (AURKA) PRO   PhosphoSitePlus   Signor 21807936
C148 Methylation IEDB 31844290
K152 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
K168 Acetylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K238 Acetylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048763 (hPHLDA1/Phos:1) pS95 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K152 M152 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K158 Q158 Biomuta DOID:1324 / lung cancer [ cosmic ]
K230 M230 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K293 R293 Biomuta DOID:1319 / brain cancer [ cosmic ]
S396 N396 Biomuta DOID:363 / uterine cancer [ cosmic ]