iPTMnet Report for Q8WUY9 (DEPDC1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUY9 / DEP1B_HUMAN
Protein Name DEP domain-containing protein 1B
Gene Name Name: DEPDC1B
Synonyms:XTP8;
Organism Homo sapiens (Human)

PRO ID PR:Q8WUY9
DAG View
PRO Name DEP domain-containing protein 1B (human)
Definition A DEP domain-containing protein 1B that is encoded in the genome of human.
Short Label hDEPDC1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUY9 (DEPDC1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K89 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus   UniProt 23186163
T178 Phosphorylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
Y417 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y442 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K89 M89 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K123 N123 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S427 F427 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S430 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S430 L430 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]