iPTMnet Report for Q8WUX9 (CHMP7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUX9 / CHMP7_HUMAN
Protein Name Charged multivesicular body protein 7
Gene Name Name: CHMP7
Organism Homo sapiens (Human)

PRO ID PR:Q8WUX9
DAG View
PRO Name charged multivesicular body protein 7 (human)
Definition A charged multivesicular body protein 7 that is encoded in the genome of human.
Short Label hCHMP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUX9 (CHMP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus   RLIMS-P 34286694
S46 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
S232 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y242 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
R405 Methylation PhosphoSitePlus
T408 Phosphorylation PhosphoSitePlus   UniProt 23186163
S410 Phosphorylation PhosphoSitePlus   UniProt 23186163
S417 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 19690332, 20068231
K427 Ubiquitination PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus   UniProt 23186163
S438 Phosphorylation phospho.ELM 18669648
S439 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 34286694, 23186163
Site PTM Type PTM Enzyme Score Source PMID
S232 Phosphorylation HPRD 18669648
S417 Phosphorylation HPRD 19651622, 20166139, 18669648, ...20068231
S429 Phosphorylation HPRD 20068231
S431 Phosphorylation HPRD 20068231
S438 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K230 N230 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K427 E427 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S438 I438 Biomuta DOID:1319 / brain cancer [ icgc ]