Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8WUW1 / BRK1_HUMAN
Protein Name Protein BRICK1
Gene Name Name: BRK1
Organism Homo sapiens (Human)

DAG View
PRO Name protein BRICK1 (human)
Definition A protein BRICK1 that is encoded in the genome of human.
Short Label hBRK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8WUW1 (BRK1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
Y21 Phosphorylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
R46 Methylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K70 Q70 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T75 A75 Biomuta DOID:10534 / stomach cancer [ tcga ]