iPTMnet Report for Q8WUW1 (BRK1)
Protein Information
UniProt AC / UniProt ID | Q8WUW1 / BRK1_HUMAN |
Protein Name | Protein BRICK1 |
Gene Name | Name: BRK1 Synonyms:C3orf10;ORFNames:HSPC300,MDS027; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WUW1 |
PRO Name | protein BRICK1 (human) |
Definition | A protein BRICK1 that is encoded in the genome of human. |
Short Label | hBRK1 |
Category | organism-gene |
Q8WUW1 (BRK1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
Y21 | Phosphorylation | score1 | PhosphoSitePlus | |||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
R46 | Methylation | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
T75 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K70 | Q70 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
T75 | A75 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |