Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUM4 / PDC6I_HUMAN
Protein Name Programmed cell death 6-interacting protein
Gene Name Name: PDCD6IP
Synonyms:AIP1,ALIX,KIAA1375;
Organism Homo sapiens (Human)

PRO ID PR:Q8WUM4
DAG View
PRO Name programmed cell death 6-interacting protein (human)
Definition A programmed cell death 6-interacting protein that is encoded in the genome of human.
Short Label hPDCD6IP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUM4 (PDCD6IP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895, 25944712
K10 Methylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
Y39 Phosphorylation PhosphoSitePlus
C40 S-Nitrosylation dbSNO 2212679, 22126794
K48 Acetylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K60 Acetylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K215 Acetylation PhosphoSitePlus   UniProt 19608861
K215 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
C250 S-Nitrosylation dbSNO 26338901
Y258 Phosphorylation PhosphoSitePlus
K269 Acetylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
Y319 Phosphorylation P12931 (SRC) IntAct   PhosphoSitePlus   RLIMS-P   Signor 22162750, 15557335
R322 Methylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K350 Acetylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
Y370 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
R456 Methylation PhosphoSitePlus
T464 Phosphorylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus   UniProt 23186163
S481 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y485 Phosphorylation PhosphoSitePlus
K486 Acetylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
R606 Methylation PhosphoSitePlus
Y608 Phosphorylation PhosphoSitePlus
T612 Phosphorylation PhosphoSitePlus
T613 Phosphorylation PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
K707 Ubiquitination PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
T724 Phosphorylation PhosphoSitePlus
Y727 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S729 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S730 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T738 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T741 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
R745 Methylation PhosphoSitePlus   UniProt 24129315
K751 Acetylation PhosphoSitePlus
K751 Methylation PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
R757 Methylation PhosphoSitePlus
R767 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y319 Phosphorylation P12931 (SRC) HPRD 15557335
S712 Phosphorylation HPRD 20068231
Y727 Phosphorylation HPRD 18669648, 20068231
S729 Phosphorylation HPRD 18669648, 20068231
S730 Phosphorylation HPRD 18669648, 20068231
T738 Phosphorylation HPRD 18669648, 20068231
T741 Phosphorylation HPRD 18669648, 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q8WUM4 (PDCD6IP) Y319 P12931 (SRC) unknown eFIP 15557335