iPTMnet Report for Q8WUM0 (NUP133)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUM0 / NU133_HUMAN
Protein Name Nuclear pore complex protein Nup133
Gene Name Name: NUP133
Organism Homo sapiens (Human)

PRO ID PR:Q8WUM0
DAG View
PRO Name nuclear pore complex protein Nup133 (human)
Definition A nuclear pore complex protein Nup133 that is encoded in the genome of human.
Short Label hNUP133
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUM0 (NUP133) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 22223895, 20068231
S7 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 18691976, 23186163, ...19007248, 19691289, 20068231
R9 Methylation PhosphoSitePlus
T10 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 20068231, 22067460
T13 Phosphorylation HPRD   PhosphoSitePlus 20068231
S15 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
R17 Methylation PhosphoSitePlus   UniProt 24129315
S27 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18847512, ...19664995, 16565220, 19651622, 22067460, 18669648, 20068231
S27 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T28 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18847512, ...19664995, 16565220, 19651622, 22067460, 18669648, 20068231
T28 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
R30 Methylation PhosphoSitePlus
T31 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 22067460, 18669648
S33 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K35 Ubiquitination PhosphoSitePlus
S41 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 20068231
S44 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18691976, 18669648, ...20068231
S45 O-Glycosylation GlyGen 33465208
S45 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...18220336, 16565220, 19651622, 22067460, 18669648, 19690332, 20068231
S50 O-Glycosylation GlyGen 33465208
S50 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...18220336, 18847512, 19664995, 19651622, 22067460, 18669648, 19690332, 20068231, 17081983
S50 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
R54 Methylation PhosphoSitePlus
S56 O-Glycosylation GlyGen 33465208
S56 Phosphorylation PhosphoSitePlus
S57 Phosphorylation HPRD   PhosphoSitePlus 19651622, 19007248
S59 O-Glycosylation GlyGen 33465208
S59 Phosphorylation HPRD   PhosphoSitePlus 19651622
S60 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 32119511, 28510447, 22121020, 33465208
S60 Phosphorylation HPRD   PhosphoSitePlus 19651622
R61 Methylation PhosphoSitePlus
T63 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 22067460
T65 Phosphorylation HPRD   PhosphoSitePlus 19651622
S72 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 22067460, 23186163, 20068231
T74 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
K82 Sumoylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
S131 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 20068231, ...22067460
T134 Phosphorylation HPRD 20068231
K135 Ubiquitination PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
S225 Phosphorylation IEDB 32387766
K239 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S267 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 22067460, 20068231
K296 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S450 Phosphorylation HPRD 20068231
C457 Methylation IEDB 31844290
S480 Phosphorylation PhosphoSitePlus   UniProt 19690332
S489 Phosphorylation HPRD   PhosphoSitePlus 19007248
S499 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
T512 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 22067460, 19691289
K518 Ubiquitination PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
S546 Phosphorylation HPRD 20068231
S547 Phosphorylation HPRD 20068231
S549 Phosphorylation HPRD 20068231
S553 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S582 Phosphorylation PhosphoSitePlus
C641 Methylation IEDB 31844290
K674 Ubiquitination PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus   UniProt 23186163
K758 Acetylation PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus
Y762 Phosphorylation PhosphoSitePlus
K787 Ubiquitination PhosphoSitePlus
Y832 Phosphorylation PhosphoSitePlus
K842 Ubiquitination PhosphoSitePlus
K913 Ubiquitination PhosphoSitePlus
T961 Phosphorylation PhosphoSitePlus
K967 Ubiquitination PhosphoSitePlus
K968 Ubiquitination PhosphoSitePlus
T969 Phosphorylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus
K991 Ubiquitination PhosphoSitePlus
S1021 Phosphorylation PhosphoSitePlus
T1027 Phosphorylation PhosphoSitePlus
Y1046 Phosphorylation PhosphoSitePlus
K1049 Ubiquitination PhosphoSitePlus
K1076 Ubiquitination PhosphoSitePlus
S1084 Phosphorylation PhosphoSitePlus
S1085 Phosphorylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus
K1089 Ubiquitination PhosphoSitePlus
K1097 Ubiquitination PhosphoSitePlus
K1107 Ubiquitination PhosphoSitePlus
K1110 Ubiquitination PhosphoSitePlus
K1123 Ubiquitination PhosphoSitePlus
S1133 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1135 Ubiquitination PhosphoSitePlus
Y1150 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T13 S13 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S15 F15 Biomuta [ cosmic ]
T31 M31 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S44 C44 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T65 I65 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S76 P76 Biomuta DOID:1319 / brain cancer [ cosmic ]
S76 F76 Biomuta DOID:4159 / skin cancer [ cosmic ]
S260 F260 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S260 C260 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S261 F261 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S303 L303 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S480 Y480 Biomuta DOID:1324 / lung cancer [ cosmic ]
T512 I512 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S546 F546 Biomuta DOID:4159 / skin cancer [ cosmic ]
S582 F582 Biomuta DOID:1324 / lung cancer [ cosmic ]
C641 S641 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S681 C681 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S755 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K787 R787 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K787 N787 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y832 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T969 P969 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1046 C1046 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1086 F1086 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]