iPTMnet Report for Q8WUH6 (TMEM263)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUH6 / TM263_HUMAN
Protein Name Transmembrane protein 263
Gene Name Name: TMEM263
Synonyms:C12orf23;
Organism Homo sapiens (Human)

PRO ID PR:Q8WUH6
DAG View
PRO Name transmembrane protein 263 (human)
Definition A transmembrane protein 263 that is encoded in the genome of human.
Short Label hTMEM263
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUH6 (TMEM263) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
T39 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S44 Phosphorylation PhosphoSitePlus
T46 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K47 Ubiquitination PhosphoSitePlus
S64 O-Glycosylation GlyGen 35254053, 28657654, 34019948, ...31373491, 28510447, 33465208, 29237092
K69 Ubiquitination PhosphoSitePlus
T70 O-Glycosylation GlyGen 35254053, 32938750, 31373491, ...34019948, 33465208, 28510447, 28657654, 29237092
T73 O-Glycosylation GlyGen 35254053, 28657654, 34019948, ...31373491, 28510447, 33465208, 29237092
T74 O-Glycosylation GlyGen 35254053, 32938750, 31373491, ...34019948, 33465208, 28510447, 28657654, 29237092
S77 O-Glycosylation GlyGen 35254053, 28657654, 34019948, ...31373491, 28510447, 33465208, 29237092
S77 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
K110 Acetylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K111 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K47 E47 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K69 T69 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]