iPTMnet Report for Q8WUH2 (TGFBRAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUH2 / TGFA1_HUMAN
Protein Name Transforming growth factor-beta receptor-associated protein 1
Gene Name Name: TGFBRAP1
Organism Homo sapiens (Human)

PRO ID PR:Q8WUH2
DAG View
PRO Name transforming growth factor-beta receptor-associated protein 1 (human)
Definition A transforming growth factor-beta receptor-associated protein 1 that is encoded in the genome of human.
Short Label hTGFBRAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUH2 (TGFBRAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K77 Ubiquitination PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
Y444 Phosphorylation PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
K592 Acetylation IEDB 34357683
Y593 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
T783 Phosphorylation PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus
T799 Phosphorylation PhosphoSitePlus
K806 Ubiquitination PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
C826 Methylation IEDB 31844290
S846 Phosphorylation PhosphoSitePlus
T849 Phosphorylation PhosphoSitePlus
S852 Phosphorylation HPRD   PhosphoSitePlus 18691976
S853 Phosphorylation HPRD   PhosphoSitePlus 20068231
S854 Phosphorylation PhosphoSitePlus
S855 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S112 L112 Biomuta DOID:4159 / skin cancer [ cosmic ]
K285 E285 Biomuta DOID:263 / kidney cancer [ cosmic ]
K344 N344 Biomuta DOID:363 / uterine cancer [ cosmic ]
S437 I437 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
T438 S438 Biomuta DOID:1324 / lung cancer [ cosmic ]
K571 R571 Biomuta DOID:363 / uterine cancer [ cosmic ]
K630 T630 Biomuta DOID:4159 / skin cancer [ cosmic ]
K815 E815 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S846 T846 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S853 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]