iPTMnet Report for Q8WUF8 (FAM172A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUF8 / F172A_HUMAN
Protein Name Cotranscriptional regulator FAM172A precursor
Gene Name Name: FAM172A
Synonyms:C5orf21;
Organism Homo sapiens (Human)

PRO ID PR:Q8WUF8
DAG View
PRO Name cotranscriptional regulator FAM172A (human)
Definition A cotranscriptional regulator FAM172A that is encoded in the genome of human.
Short Label hFAM172A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUF8 (FAM172A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K35 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
K412 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K49 N49 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K185 E185 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S215 L215 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]
Y260 C260 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]