iPTMnet Report for Q8WUF5 (PPP1R13L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUF5 / IASPP_HUMAN
Protein Name RelA-associated inhibitor
Gene Name Name: PPP1R13L
Synonyms:IASPP,NKIP1,PPP1R13BL,RAI;
Organism Homo sapiens (Human)

PRO ID PR:Q8WUF5
DAG View
PRO Name RelA-associated inhibitor (human)
Definition A RelA-associated inhibitor that is encoded in the genome of human.
Short Label hPPP1R13L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUF5 (PPP1R13L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S19 Phosphorylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S53 Phosphorylation HPRD   PhosphoSitePlus 20068231
S65 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S81 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
R82 Methylation PhosphoSitePlus
S84 Phosphorylation P06493 (CDK1) HPRD   PhosphoSitePlus   RLIMS-P   Signor   UniProt 30105797, 23186163, 20068231
K87 Methylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus   UniProt 23186163
S102 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y109 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
S110 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 16964243, ...20068231
S113 Phosphorylation P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 16964243, 30105797, ...19651622, 18669648, 20068231, 18212344
R117 Methylation PhosphoSitePlus
S119 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S120 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
R122 Methylation PhosphoSitePlus
T123 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
Y126 Phosphorylation PhosphoSitePlus
Y132 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S134 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18212344, 19664995, ...18452278, 18669648
R137 Methylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
R142 Methylation IEDB   PhosphoSitePlus 27503676
R144 Methylation PhosphoSitePlus
S152 Phosphorylation HPRD   PhosphoSitePlus 18212344
R155 Methylation PhosphoSitePlus
S158 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
R160 Methylation PhosphoSitePlus
R167 Methylation PhosphoSitePlus   UniProt 24129315
T173 Phosphorylation PhosphoSitePlus
R180 Methylation PhosphoSitePlus   UniProt 24129315
S183 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243, 20068231, ...19690332
R185 Methylation PhosphoSitePlus
S187 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...20068231, 18212344
R200 Methylation PhosphoSitePlus
S203 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
R205 Methylation PhosphoSitePlus
T209 O-Glycosylation GlyGen 31492838, 35254053
T209 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S216 O-Glycosylation GlyGen 31492838, 35254053
S216 Phosphorylation PhosphoSitePlus
S220 Phosphorylation HPRD   phospho.ELM 18669648
S225 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
R235 Methylation PhosphoSitePlus
T241 Phosphorylation HPRD   PhosphoSitePlus 18212344
R243 Methylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
S280 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S282 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus   UniProt 23186163
K314 Methylation PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
S316 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S320 Phosphorylation PhosphoSitePlus
S332 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18212344
S335 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus   UniProt 23186163
T341 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18212344
R344 Methylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S357 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S358 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
R362 Methylation PhosphoSitePlus
S395 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T399 Phosphorylation PhosphoSitePlus
R400 Methylation PhosphoSitePlus
T491 Phosphorylation PhosphoSitePlus
K522 Methylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
S526 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K541 Ubiquitination PhosphoSitePlus
Y543 Phosphorylation PhosphoSitePlus
S567 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18220336, 19651622, 18669648, 20068231
S594 Phosphorylation HPRD   phospho.ELM 18669648
S597 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S604 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S48 L48 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S74 L74 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S81 I81 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S100 L100 Biomuta DOID:4159 / skin cancer [ cosmic ]
S110 N110 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S119 P119 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S120 P120 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R122 C122 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R122 H122 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T123 I123 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y132 H132 Biomuta DOID:2531 / hematologic cancer [ icgc ]
R144 C144 Biomuta DOID:4159 / skin cancer [ cosmic ]
R144 H144 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
R144 S144 Biomuta DOID:3571 / liver cancer [ cosmic ]
S152 P152 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R180 C180 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R185 H185 Biomuta DOID:9256 / colorectal cancer [ icgc ]
R235 C235 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R243 H243 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R243 C243 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
R243 G243 Biomuta DOID:2394 / ovarian cancer [ icgc ]
S253 F253 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y269 C269 Biomuta DOID:5158 / pleural cancer [ cosmic ]
K314 N314 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R344 C344 Biomuta DOID:1324 / lung cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
S357 P357 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S357 F357 Biomuta DOID:4159 / skin cancer [ cosmic ]
S358 R358 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S358 N358 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R362 P362 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R362 C362 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ icgc ]
T491 M491 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S526 F526 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ]
S616 F616 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]