iPTMnet Report for Q8WU79 (SMAP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WU79 / SMAP2_HUMAN
Protein Name Stromal membrane-associated protein 2
Gene Name Name: SMAP2
Synonyms:SMAP1L;
Organism Homo sapiens (Human)

PRO ID PR:Q8WU79
DAG View
PRO Name stromal membrane-associated protein 2 (human)
Definition A stromal membrane-associated protein 2 that is encoded in the genome of human.
Short Label hSMAP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WU79 (SMAP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
C28 Methylation IEDB 31844290
S67 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
Y96 Phosphorylation PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus   UniProt 23186163
K135 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S180 O-Glycosylation GlyGen 28604694
S180 Phosphorylation PhosphoSitePlus
T181 O-Glycosylation GlyGen 28604694
T181 Phosphorylation PhosphoSitePlus
S197 O-Glycosylation GlyGen 31492838, 35254053, 34019948, ...28604694, 32119511, 29351928, 28657654
T203 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S219 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S221 Phosphorylation phospho.ELM 18669648
S222 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus   UniProt 23186163
S225 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S231 Phosphorylation PhosphoSitePlus   UniProt 24275569
T234 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
Site PTM Type PTM Enzyme Score Source PMID
Y96 Phosphorylation HPRD 19901323
S219 Phosphorylation HPRD 18691976, 20230923, 20058876, ...19651622, 18669648, 20068231
S221 Phosphorylation HPRD 18669648, 20068231
S231 Phosphorylation HPRD 20166139
T234 Phosphorylation HPRD 20166139
S240 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y96 C96 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y96 H96 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S127 R127 Biomuta DOID:3571 / liver cancer [ cosmic ]
S180 P180 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S197 F197 Biomuta DOID:4159 / skin cancer [ cosmic ]
S223 F223 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S231 Y231 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S231 F231 Biomuta DOID:4362 / cervical cancer [ icgc ]