iPTMnet Report for Q8WU20 (FRS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WU20 / FRS2_HUMAN
Protein Name Fibroblast growth factor receptor substrate 2
Gene Name Name: FRS2
Organism Homo sapiens (Human)

PRO ID PR:Q8WU20
DAG View
PRO Name fibroblast growth factor receptor substrate 2 (human)
Definition A fibroblast growth factor receptor substrate 2 that is encoded in the genome of human.
Short Label hFRS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WU20 (FRS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 10092678, 9660748
T49 Phosphorylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
T132 Phosphorylation PRO   PhosphoSitePlus
T135 Phosphorylation PRO   PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PRO   PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus   UniProt 24275569
T183 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PRO   PhosphoSitePlus   RLIMS-P 24445144
T200 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus   UniProt 23186163
S221 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
S226 Phosphorylation PhosphoSitePlus
T227 Phosphorylation HPRD   PhosphoSitePlus 18669648
K267 Ubiquitination PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PRO   PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S316 Phosphorylation HPRD 20068231
T326 Phosphorylation PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
T328 Phosphorylation PhosphoSitePlus
S329 O-Glycosylation GlyGen 31492838, 35132862
S329 Phosphorylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PRO   PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus   UniProt 23186163
T376 Phosphorylation PRO
S378 Phosphorylation PhosphoSitePlus
Y392 Phosphorylation PRO   PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
Y436 Phosphorylation IntAct   PRO   PhosphoSitePlus 9632781
S445 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
T452 Phosphorylation PRO
T455 Phosphorylation PRO   PhosphoSitePlus
T457 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PRO   PhosphoSitePlus
T463 Phosphorylation PRO   PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
T468 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y471 Phosphorylation PRO   PhosphoSitePlus
T479 Phosphorylation HPRD 20068231
S483 Phosphorylation HPRD 20068231
T499 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
T504 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000026214 (hFRS2/InitMet-/Phos:1) pY196,pY306,pY349,pY392,pY436,pY471 PRO
PR:000047449 (hFRS2/InitMet-/Phos:2) pT132,pT135,pT138,pT376,pT452,pT455,pT458,pT463 PRO