Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WU17 / RN139_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF139
Gene Name Name: RNF139
Synonyms:TRC8;
Organism Homo sapiens (Human)

PRO ID PR:Q8WU17
DAG View
PRO Name E3 ubiquitin-protein ligase RNF139 (human)
Definition An E3 ubiquitin-protein ligase RNF139 that is encoded in the genome of human.
Short Label hRNF139
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WU17 (RNF139) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
T228 Phosphorylation PhosphoSitePlus
Y449 Phosphorylation PhosphoSitePlus
Y450 Phosphorylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
S625 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S634 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T635 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T663 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18767875, 19413330, 19415658, 18669648, 19690332, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T228 K228 Biomuta DOID:1324 / lung cancer [ tcga ]