iPTMnet Report for Q8WU17 (RNF139)
Protein Information
| UniProt AC / UniProt ID | Q8WU17 / RN139_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase RNF139 |
| Gene Name | Name: RNF139 Synonyms:TRC8; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WU17 |
| PRO Name | E3 ubiquitin-protein ligase RNF139 (human) |
| Definition | An E3 ubiquitin-protein ligase RNF139 that is encoded in the genome of human. |
| Short Label | hRNF139 |
| Category | organism-gene |
DAG ViewQ8WU17 (RNF139) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| T228 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y449 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y450 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K528 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S531 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S625 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
| S634 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
| T635 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
| T663 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 19413330, 18691976, 21406692, ... |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T228 | K228 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
