iPTMnet Report for Q8WU10 (PYROXD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WU10 / PYRD1_HUMAN
Protein Name Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
Gene Name Name: PYROXD1
Organism Homo sapiens (Human)

PRO ID PR:Q8WU10
DAG View
PRO Name pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (human)
Definition A pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 that is encoded in the genome of human.
Short Label hPYROXD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WU10 (PYROXD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
K54 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K225 Acetylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
Y354 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K88 N88 Biomuta DOID:1324 / lung cancer [ cosmic ]
K91 N91 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K287 T287 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]