iPTMnet Report for Q8WTW3 (COG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WTW3 / COG1_HUMAN
Protein Name Conserved oligomeric Golgi complex subunit 1
Gene Name Name: COG1
Synonyms:KIAA1381,LDLB;
Organism Homo sapiens (Human)

PRO ID PR:Q8WTW3
DAG View
PRO Name conserved oligomeric Golgi complex subunit 1 (human)
Definition A conserved oligomeric Golgi complex subunit 1 that is encoded in the genome of human.
Short Label hCOG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WTW3 (COG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
T3 Phosphorylation PhosphoSitePlus
T6 Phosphorylation HPRD   PhosphoSitePlus 18691976
S7 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163, 19691289
K11 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K377 Methylation PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
S459 Phosphorylation HPRD   PhosphoSitePlus 18691976
K528 Acetylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus
K553 Ubiquitination PhosphoSitePlus
R559 Methylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
K607 Ubiquitination PhosphoSitePlus
T657 Phosphorylation HPRD   PhosphoSitePlus 18077418
K666 Ubiquitination PhosphoSitePlus
C753 Methylation IEDB 31844290
Y811 Phosphorylation PhosphoSitePlus
S890 Phosphorylation PhosphoSitePlus
S891 Phosphorylation PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
K933 Ubiquitination PhosphoSitePlus
S959 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T6 A6 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S459 F459 Biomuta DOID:363 / uterine cancer [ icgc ]
T657 I657 Biomuta DOID:4159 / skin cancer [ cosmic ]
S959 G959 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]